Aspirin for Dog
Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Aspirin is used in dog for Anti-platelet (low-dose), pain/inflammation. Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Aspirin in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Bufferin, Ascriptin
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.5–1 mg/kg | q24h (antiplatelet) | Long-term for antiplatelet | Anti-platelet (low-dose), pain/inflammation | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Irreversibly acetylates cyclooxygenase (COX-1 and COX-2), inhibiting prostaglandin and thromboxane synthesis.
Side effects & warnings
TOXIC to cats (prolonged half-life, deficient glucuronidation). Use buffered only. GI ulceration. Avoid with other NSAIDs or corticosteroids. Platelet inhibition irreversible.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Analgesic drugs with dog dosing
Aspirin dosing in other species
Why a species-specific page? Aspirin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.