ExoticRx · exoticrx.com/drugs/aspirin
US brand names:Bufferin, Ascriptin
Aspirin is dosed at 0.5–1 mg/kg PO q24h (antiplatelet) in dogs, per BSAVA Small Animal Formulary 10th ed., Part A: Canine and Feline (Allerton F, ed.), Aspirin monograph, printed p.33 (corpus p.49). Verify against current literature before clinical use.
Irreversibly acetylates cyclooxygenase (COX-1 and COX-2), inhibiting prostaglandin and thromboxane synthesis.
TOXIC to cats (prolonged half-life, deficient glucuronidation). Use buffered only. GI ulceration. Avoid with other NSAIDs or corticosteroids. Platelet inhibition irreversible.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
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