ExoticRx · exoticrx.com/drugs/carprofen
US brand names:Rimadyl, Novox
Carprofen is dosed at 1–4 mg/kg PO, SC, IM, IV q24h, follow with half the dose q24-72h in ball pythons, per Lawton MP.C. Pain management after surgery. Proc North Am Vet Conf; 1999:782. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.252 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.6 (Analgesic (Including Antiinflammatory) Agents Used in Reptiles). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Verify against current literature before clinical use.
Preferentially inhibits COX-2, reducing prostaglandin synthesis at sites of inflammation while relatively sparing COX-1 (GI, renal, platelet).
Hepatotoxicity reported (especially Labrador Retrievers). Monitor liver enzymes. GI ulceration risk. Avoid in cats (limited safety data). Not for use with other NSAIDs.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 28 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | SC | 4.4 mg/kg | Single dose preop | Strong | RIMADYL - Carprofen Tablet, Chewable [US Product Label]. Zoetis; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=27197d3c-8e25-4e78-b83b-ee26f9249369 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.219 (2026-08-01). — Plumb's 10th ed (held) printed p.192, Carprofen monograph spanning p.190-192; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| Dog (Domestic) | PO | 2.2–4.4 mg/kg | q24h | Strong |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.
Species references:All African Grey Parrot drugsAll African Pygmy Hedgehog drugsAll Ball Python drugsAll Bearded Dragon drugsAll Blue-and-Gold Macaw drugsAll Blue-tongue Skink drugsAll Chicken (Poultry) drugsAll Chinchilla drugsAll Corn Snake drugsAll Crested Gecko drugsAll Dog (Domestic) drugsAll Dwarf Hamster drugsAll Eastern Box Turtle drugsAll Ferret drugsAll Gerbil drugsAll Green-cheeked Conure drugsAll Guinea Pig drugsAll Lovebird drugsAll Mouse drugsAll Pet Rat drugsAll Rabbit (Domestic) drugsAll Red-eared Slider drugsAll Russian Tortoise drugsAll Sugar Glider drugsAll Sulcata Tortoise drugsAll Syrian Hamster drugsAll Umbrella Cockatoo drugsAll Zebra Finch drugs
| RIMADYL - Carprofen Injection [US Product Label]. Zoetis. DailyMed setid 27197d3c-8e25-4e78-b83b-ee26f9249369. Plus Plumb's 10th ed printed p.192 DOGS (oral route as served). |