ExoticRx · exoticrx.com/drugs/carprofen
US brand names:Rimadyl, Novox
Carprofen is dosed at 5 mg/kg IM for 3 days in zebra finches, per Edling TM. Anaesthesia and analgesia. In: Chitty J, Harcourt-Brown N, eds. BSAVA Manual of Psittacine Birds; British Small Animal Veterinary Association, Gloucester, UK; 2005:87-96. — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.458 (2026-08-01).. Verify against current literature before clinical use.
Preferentially inhibits COX-2, reducing prostaglandin synthesis at sites of inflammation while relatively sparing COX-1 (GI, renal, platelet).
Hepatotoxicity reported (especially Labrador Retrievers). Monitor liver enzymes. GI ulceration risk. Avoid in cats (limited safety data). Not for use with other NSAIDs.
Species references:All Dog (Domestic) drugsAll Mouse drugsAll Syrian Hamster drugsAll Zebra Finch drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | SC | 4.4 mg/kg | Single dose preop | Strong | RIMADYL - Carprofen Tablet, Chewable [US Product Label]. Zoetis; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=27197d3c-8e25-4e78-b83b-ee26f9249369 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.219 (2026-08-01). |
| Dog (Domestic) | PO | 2.2–4.4 mg/kg | q12-24h | Strong | RIMADYL - Carprofen Tablet, Chewable [US Product Label]. Zoetis; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=27197d3c-8e25-4e78-b83b-ee26f9249369 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.219 (2026-08-01). |
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