ExoticRx · exoticrx.com/drugs/colchicine
US brand names:Colcrys
Colchicine is dosed at 0.01–0.03 mg/kg PO q24h in dogs, per Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.337 (2026-08-01).. Verify against current literature before clinical use.
Binds tubulin disrupting microtubule formation. Inhibits neutrophil migration and reduces inflammation. Anti-fibrotic properties in hepatic fibrosis.
Narrow therapeutic index. GI toxicity (nausea, vomiting, diarrhea) common. Used for hepatic fibrosis and amyloidosis in Shar Peis. Bone marrow suppression at toxic doses.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.