Cat · Felis catus · typical adult weight 2.50–7.00 kg
Colchicine is dosed at 0.01–0.03 mg/kg PO q24h in cats, per Papich MG. Saunders Handbook of Veterinary Drugs, Colchicine, Small Animal Dosage, printed p.185 (corpus PDF p.213) - "Dogs and Cats - 0.01-0.03 mg/kg q24h PO." [CORRECTED - Plumb's 10th ed printed p.309-311 carries DOGS and BIRDS headings only and has NO cats row, so the cited page does not carry this rule. The served 0.01 low bound coincidentally equals plumb's BIRD low - that resemblance is not the source.] CAVEAT from papich printed p.184 - "the efficacy for controlling liver fibrosis in chronic liver disease is questionable and unproven".. Colchicine is used in cats for Hepatic fibrosis. Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Colchicine in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Colcrys
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.01–0.03 mg/kg | q24h | Long-term | Hepatic fibrosis | Weak | Papich MG. Saunders Handbook of Veterinary Drugs, Colchicine, Small Animal Dosage, printed p.185 (corpus PDF p.213) - "Dogs and Cats - 0.01-0.03 mg/kg q24h PO." [CORRECTED - Plumb's 10th ed printed p.309-311 carries DOGS and BIRDS headings only and has NO cats row, so the cited page does not carry this rule. The served 0.01 low bound coincidentally equals plumb's BIRD low - that resemblance is not the source.] CAVEAT from papich printed p.184 - "the efficacy for controlling liver fibrosis in chronic liver disease is questionable and unproven". |
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Binds tubulin disrupting microtubule formation. Inhibits neutrophil migration and reduces inflammation. Anti-fibrotic properties in hepatic fibrosis.
Narrow therapeutic index. GI toxicity (nausea, vomiting, diarrhea) common. Used for hepatic fibrosis and amyloidosis in Shar Peis. Bone marrow suppression at toxic doses.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Colchicine dose range in cats, with cited source references: PO 0.01–0.03 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Colchicine in cats: PO.
Cited course lengths for Colchicine in cats include: Long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Colchicine is indicated in cats for: Hepatic fibrosis.
These are general warnings for Colchicine across species; consult the cat dosing table above for species-specific guidance. Narrow therapeutic index. GI toxicity (nausea, vomiting, diarrhea) common. Used for hepatic fibrosis and amyloidosis in Shar Peis. Bone marrow suppression at toxic doses.
Why a species-specific page? Colchicine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.