Dimethyl Sulfoxide for Dog
Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Dimethyl Sulfoxide is used in dog for Musculoskeletal inflammation. Routes documented in dog: Topical. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Dimethyl Sulfoxide in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: DMSO, Domoso
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| Topical | 0 mg/kg | q8-12h topical | Variable | Musculoskeletal inflammation | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Hydroxyl radical scavenger and membrane penetrant. Anti-inflammatory, analgesic, and carrier properties (enhances penetration of other drugs through skin).
Side effects & warnings
Garlic/oyster breath after topical application (excreted via lungs). Wear gloves (carries dissolved substances through handler's skin). FDA-approved for horses only.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Analgesic drugs with dog dosing
Dimethyl Sulfoxide dosing in other species
Why a species-specific page? Dimethyl Sulfoxide pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.