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Dimethyl Sulfoxide for Horse

Equine · Equus caballus · typical adult weight 350.00–700.00 kg

Dimethyl Sulfoxide is used in horse for Acute musculoskeletal inflammation. Routes documented in horse: TOPICAL. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 1 cited dose rule for Dimethyl Sulfoxide in horse, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: DMSO, Domoso

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
TOPICAL100 mg/cm2 topicallyq12-24h3-5 daysAcute musculoskeletal inflammationStrongFDA NADA Label

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These ranges are per kg. Enter your horse's weight to get the precise dose and draw-up volume — unit and concentration math done for you.

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Mechanism of action

Hydroxyl radical scavenger and membrane penetrant. Anti-inflammatory, analgesic, and carrier properties (enhances penetration of other drugs through skin).

Side effects & warnings

Garlic/oyster breath after topical application (excreted via lungs). Wear gloves (carries dissolved substances through handler's skin). FDA-approved for horses only.

Species-specific contraindications and adverse-reaction reports for horse may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Analgesic drugs with horse dosing

Dimethyl Sulfoxide dosing in other species

Why a species-specific page? Dimethyl Sulfoxide pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horse — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.