Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Ceftriaxone is dosed at 25–50 mg/kg SC q12-24h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed — Ceftriaxone, Dosages, DOGS, printed p.231 (corpus PDF p.258). Underlying reference 6 = Rebuelto M, Albarellos G, Ambros L. Pharmacokinetics of ceftriaxone administered by the intravenous, intramuscular and subcutaneous routes to dogs. J Vet Pharmacol Ther. 2002;25:73-76.. Ceftriaxone is used in dogs for Severe bacterial infections / sepsis. Routes documented in dogs: SC. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Ceftriaxone in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Rocephin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| SC | 25–50 mg/kg | q12-24h | 7-14 days | Severe bacterial infections / sepsis | Strong | Plumb's Veterinary Drug Handbook, 9th Ed — Ceftriaxone, Dosages, DOGS, printed p.231 (corpus PDF p.258). Underlying reference 6 = Rebuelto M, Albarellos G, Ambros L. Pharmacokinetics of ceftriaxone administered by the intravenous, intramuscular and subcutaneous routes to dogs. J Vet Pharmacol Ther. 2002;25:73-76. |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds PBPs inhibiting cell wall synthesis. Long half-life allows once-daily dosing. Excellent CSF penetration.
Do not mix with calcium-containing solutions. Biliary pseudolithiasis possible. Adjust in hepatic/renal compromise.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Ceftriaxone dose range in dogs, with cited source references: SC 25–50 mg/kg q12-24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Ceftriaxone in dogs: SC.
Cited course lengths for Ceftriaxone in dogs include: 7-14 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Ceftriaxone is indicated in dogs for: Severe bacterial infections / sepsis.
These are general warnings for Ceftriaxone across species; consult the dog dosing table above for species-specific guidance. Do not mix with calcium-containing solutions. Biliary pseudolithiasis possible. Adjust in hepatic/renal compromise.
Why a species-specific page? Ceftriaxone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.