ExoticRx · exoticrx.com/drugs/ceftriaxone
US brand names:Rocephin
Ceftriaxone is dosed at 75–100 mg/kg IM q4-8h in african grey parrots, per 391. Hawkins MG, Barron H, Speer BL, et al. Birds. In: Carpenter JW, eds. Exotic Animal Formulary, 4th ed., Elsevier Saunders, St. Louis, MO; 2013:183-437. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.408 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.1 (Antimicrobial Agents Used in Birds.a). Verify against current literature before clinical use.
Binds PBPs inhibiting cell wall synthesis. Long half-life allows once-daily dosing. Excellent CSF penetration.
Do not mix with calcium-containing solutions. Biliary pseudolithiasis possible. Adjust in hepatic/renal compromise.
Species references:All African Grey Parrot drugsAll Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 3 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | SC | 25–50 mg/kg | q12-24h | Strong | Plumb's Veterinary Drug Handbook, 10th ed (2023) — Ceftriaxone, Dosages, DOGS, printed p.231. Underlying reference 6 = Rebuelto M, Albarellos G, Ambros L. Pharmacokinetics of ceftriaxone administered by the intravenous, intramuscular and subcutaneous routes to dogs. J Vet Pharmacol Ther. 2002;25:73-76.Compilation only — we have not located an independent source that prints this figure. |
| Cat (Domestic) | SC | 25 mg/kg | q12-24h | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023) — Ceftriaxone, Dosages, CATS, printed p.231. Underlying reference 7 = Albarellos GA, Kreil VE, Landoni MF. Pharmacokinetics of ceftriaxone after intravenous, intramuscular and subcutaneous administration to domestic cats. J Vet Pharmacol Ther. 2007;30(4):345-352.Compilation only — we have not located an independent source that prints this figure. |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.