Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Indoxacarb is dosed at / Cats: Fleas: 25 mg/kg (equivalent to 0.128 ml/kg Activyl) in dogs, per BSAVA Small Animal Formulary, 10th Ed (2020), Part A — Canine and Feline, p.223-224 — Indoxacarb (Activyl, Activyl Tick Plus), DOSES, Dogs. — LOCATOR CONVENTION 2026-08-07: the bare 'p.223' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.207; verified by finding the drug named there. If you are holding the book, turn to p.207. — SOURCE EDITION: BSAVA Small Animal Formulary, Part A — Canine and Feline — ISBN 9781910443705, https://openlibrary.org/isbn/9781910443705. Indoxacarb is used in dogs for Flea control. Routes documented in dogs: TOPICAL. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Indoxacarb in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Activyl
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| TOPICAL | / Cats: Fleas: 25 mg/kg (equivalent to 0.128 ml/kg Activyl) | q30 days | Monthly | Flea control | Moderate | BSAVA Small Animal Formulary, 10th Ed (2020), Part A — Canine and Feline, p.223-224 — Indoxacarb (Activyl, Activyl Tick Plus), DOSES, Dogs. — LOCATOR CONVENTION 2026-08-07: the bare 'p.223' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.207; verified by finding the drug named there. If you are holding the book, turn to p.207. — SOURCE EDITION: BSAVA Small Animal Formulary, Part A — Canine and Feline — ISBN 9781910443705, https://openlibrary.org/isbn/9781910443705 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 15 | IV | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.224 | 15 mg/kg (equivalent to 0.077 ml/kg Activyl or 0.1 ml/ kg Activyl Tick Plus). Apply monthly |
| Dose (ml/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.077 | IV | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.224 | 15 mg/kg (equivalent to 0.077 ml/kg Activyl or 0.1 ml/ kg Activyl Tick Plus). Apply monthly |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Bioactivated by flea enzymes to its active metabolite, which blocks sodium channels causing paralysis and death. Flea-activated (low mammalian toxicity).
Dogs and cats. Monthly topical. Safe for puppies/kittens >8 weeks. May take 8 hours for full flea kill. Lower environmental flea burden important.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Indoxacarb dose range in dogs, with cited source references: TOPICAL / Cats: Fleas: 25 mg/kg (equivalent to 0.128 ml/kg Activyl) q30 days. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Indoxacarb in dogs: TOPICAL.
Cited course lengths for Indoxacarb in dogs include: Monthly. Duration depends on the indication — match it to the specific dose rule in the table above.
Indoxacarb is indicated in dogs for: Flea control.
These are general warnings for Indoxacarb across species; consult the dog dosing table above for species-specific guidance. Dogs and cats. Monthly topical. Safe for puppies/kittens >8 weeks. May take 8 hours for full flea kill. Lower environmental flea burden important.
Why a species-specific page? Indoxacarb pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.