Doxapram for Dog
Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Doxapram is used in dog for Neonatal resuscitation, post-anesthetic apnea, Neonatal puppy resuscitation (cesarean section), Neonatal resuscitation, post-anesthetic respiratory depression. Routes documented in dog: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 3 cited dose rules for Doxapram in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Dopram
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 1–5 mg/kg | once | Single dose; may repeat | Neonatal resuscitation, post-anesthetic apnea | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| IV | 1–2 mg/kg | once | Single dose | Neonatal puppy resuscitation (cesarean section) | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| IV | 1–5 mg/kg | IV or sublingual | Single dose, repeat once if needed | Neonatal resuscitation, post-anesthetic respiratory depression | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Stimulates peripheral carotid chemoreceptors and central medullary respiratory centers, increasing tidal volume and respiratory rate.
Side effects & warnings
Short duration of action (minutes). Use for neonatal resuscitation or post-anesthetic apnea. May cause hypertension, tachycardia, and seizures at high doses. Ensure adequate airway before use.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Respiratory drugs with dog dosing
Doxapram dosing in other species
Why a species-specific page? Doxapram pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.