Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Codeine is dosed at 0.5–2 mg/kg PO q6-12h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Codeine is used in dogs for Antitussive. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Codeine in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.5–2 mg/kg | q6-12h | Short-term | Antitussive | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mu-opioid receptor agonist (prodrug converted to morphine by CYP2D6). Suppresses cough reflex in medullary cough center. Mild analgesic.
DEA Schedule II (alone) or V (in combination). Variable CYP2D6 metabolism across species. Constipation, sedation. Poor analgesic in dogs (CYP2D6 polymorphism).
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Codeine dose range in dogs, with cited source references: PO 0.5–2 mg/kg q6-12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Codeine in dogs: PO.
Cited course lengths for Codeine in dogs include: Short-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Codeine is indicated in dogs for: Antitussive.
These are general warnings for Codeine across species; consult the dog dosing table above for species-specific guidance. DEA Schedule II (alone) or V (in combination). Variable CYP2D6 metabolism across species. Constipation, sedation. Poor analgesic in dogs (CYP2D6 polymorphism).
Why a species-specific page? Codeine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.