Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Clemastine is dosed at 0.05–0.1 mg/kg PO q12h in dogs, per Miller WH, Scott DW, Wellington JR. A clinical-trial on the efficacy of clemastine in the management of allergic pruritus in dogs. Canadian Veterinary Journal-Revue Veterinaire Canadienne. 1993;34:25-27. PMID: 17424141 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.307 (2026-08-01). — Plumb's 10th ed (held) printed p.279, Clemastine monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Clemastine is used in dogs for Atopic dermatitis / allergic rhinitis. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Clemastine in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Tavist, Dayhist
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.05–0.1 mg/kg | q12h | Long-term for allergy management; reassess seasonally | Atopic dermatitis / allergic rhinitis | Moderate | Miller WH, Scott DW, Wellington JR. A clinical-trial on the efficacy of clemastine in the management of allergic pruritus in dogs. Canadian Veterinary Journal-Revue Veterinaire Canadienne. 1993;34:25-27. PMID: 17424141 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.307 (2026-08-01). — Plumb's 10th ed (held) printed p.279, Clemastine monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.05–0.1 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.106 | 0.05-0.1 mg/kg p.o. q12h |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Competitive H1 histamine receptor antagonist that blocks histamine-mediated allergic responses including pruritus, urticaria, and rhinitis.
Sedation is common. Anticholinergic effects (dry mouth, urinary retention). May be more effective than diphenhydramine for canine atopic dermatitis.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Clemastine dose range in dogs, with cited source references: PO 0.05–0.1 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Clemastine in dogs: PO.
Cited course lengths for Clemastine in dogs include: Long-term for allergy management; reassess seasonally. Duration depends on the indication — match it to the specific dose rule in the table above.
Clemastine is indicated in dogs for: Atopic dermatitis / allergic rhinitis.
These are general warnings for Clemastine across species; consult the dog dosing table above for species-specific guidance. Sedation is common. Anticholinergic effects (dry mouth, urinary retention). May be more effective than diphenhydramine for canine atopic dermatitis.
Why a species-specific page? Clemastine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.