Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Pentoxifylline (Respiratory) is dosed at 10–25 mg/kg PO q8-12h in dogs, per Koch S, Torres S, Plumb D. Small Animal Dermatology Drug Handbook. Wiley-Blackwell; 2012. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1030 (2026-08-01).. Pentoxifylline (Respiratory) is used in dogs for Pulmonary fibrosis / vasculitis adjunct. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Pentoxifylline (Respiratory) in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Trental
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 10–25 mg/kg | q8-12h | Long-term; months to assess efficacy | Pulmonary fibrosis / vasculitis adjunct | Moderate | Koch S, Torres S, Plumb D. Small Animal Dermatology Drug Handbook. Wiley-Blackwell; 2012. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1030 (2026-08-01). |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Non-selective phosphodiesterase inhibitor that improves red blood cell deformability, reduces blood viscosity, and inhibits TNF-alpha and neutrophil activation in pulmonary vasculature.
GI upset at initiation. Used for pulmonary fibrosis and chronic bronchitis adjunct therapy. Anti-inflammatory effects complement bronchodilators.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Pentoxifylline (Respiratory) dose range in dogs, with cited source references: PO 10–25 mg/kg q8-12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Pentoxifylline (Respiratory) in dogs: PO.
Cited course lengths for Pentoxifylline (Respiratory) in dogs include: Long-term; months to assess efficacy. Duration depends on the indication — match it to the specific dose rule in the table above.
Pentoxifylline (Respiratory) is indicated in dogs for: Pulmonary fibrosis / vasculitis adjunct.
These are general warnings for Pentoxifylline (Respiratory) across species; consult the dog dosing table above for species-specific guidance. GI upset at initiation. Used for pulmonary fibrosis and chronic bronchitis adjunct therapy. Anti-inflammatory effects complement bronchodilators.
Why a species-specific page? Pentoxifylline (Respiratory) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.