Acetylcysteine for Dog
Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Acetylcysteine is used in dog for Acetaminophen toxicity (antidote), Mucolytic. Routes documented in dog: IV, Nebulization. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Acetylcysteine in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Mucomyst, ACC
Dose ranges
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Breaks disulfide bonds in mucus glycoproteins reducing viscosity (mucolytic). Also a glutathione precursor providing hepatoprotection (acetaminophen antidote).
Side effects & warnings
Dual role: mucolytic (nebulized/oral) and acetaminophen antidote (IV/oral). Bronchospasm possible with nebulization — pretreat with bronchodilator. Foul smell.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Respiratory drugs with dog dosing
Acetylcysteine dosing in other species
Why a species-specific page? Acetylcysteine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.