Aminophylline for Dog
Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Aminophylline is used in dog for Acute bronchospasm, Bronchodilation, chronic bronchitis, Collapsing trachea adjunct. Routes documented in dog: IV, PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 3 cited dose rules for Aminophylline in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 5–10 mg/kg | q8h | As needed | Acute bronchospasm | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 10–11 mg/kg | q8h | Chronic as needed | Bronchodilation, chronic bronchitis | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 10–11 mg/kg | q8h | Chronic | Collapsing trachea adjunct | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Phosphodiesterase inhibitor and adenosine receptor antagonist. Relaxes bronchial smooth muscle, stimulates respiratory drive, and has mild diuretic effect.
Side effects & warnings
Narrow therapeutic index. Monitor for tachycardia, GI upset, CNS stimulation, and seizures. Avoid concurrent fluoroquinolones (decreased metabolism). IV administration must be slow.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Respiratory drugs with dog dosing
Aminophylline dosing in other species
Why a species-specific page? Aminophylline pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.