Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Aminophylline is dosed at 5–10 mg/kg IV q8h in dogs, per Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.82 (2026-08-01). — Plumb's 10th ed (held) printed p.53, Aminophylline monograph spanning p.53-55; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Aminophylline is used in dogs for Acute bronchospasm, Bronchodilation, chronic bronchitis, Collapsing trachea adjunct. Routes documented in dogs: IV, PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 3 cited dose rules for Aminophylline in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 5–10 mg/kg | q8h | As needed | Acute bronchospasm | Moderate | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.82 (2026-08-01). — Plumb's 10th ed (held) printed p.53, Aminophylline monograph spanning p.53-55; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| PO | 10–11 mg/kg | q8h | Chronic as needed | Bronchodilation, chronic bronchitis | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.53, Aminophylline monograph spanning p.53-55; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — figure located 2026-08-05 at Plumb's 10th ed printed p.54, Aminophylline monograph; the page cited previously does not carry it. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| PO | 10–11 mg/kg | q8h | Chronic | Collapsing trachea adjunct | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.53, Aminophylline monograph spanning p.53-55; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — figure located 2026-08-05 at Plumb's 10th ed printed p.54, Aminophylline monograph; the page cited previously does not carry it. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 10 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.36 | 10 mg/kg p.o. q8h or slowly i.v. (diluted) for emergency bronchodilation |
| 10 | IM | Papich Saunders Handbook of Veterinary Drugs, 4th edp.58 | • 10 mg/kg q8h IM, or IV. • 6.6 mg/kg q12h, IM or IV. |
| 6.6 | IM | Papich Saunders Handbook of Veterinary Drugs, 4th edp.58 | • 10 mg/kg q8h IM, or IV. • 6.6 mg/kg q12h, IM or IV. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Phosphodiesterase inhibitor and adenosine receptor antagonist. Relaxes bronchial smooth muscle, stimulates respiratory drive, and has mild diuretic effect.
Narrow therapeutic index. Monitor for tachycardia, GI upset, CNS stimulation, and seizures. Avoid concurrent fluoroquinolones (decreased metabolism). IV administration must be slow.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Aminophylline dose ranges in dogs, with cited source references: IV 5–10 mg/kg q8h; PO 10–11 mg/kg q8h; PO 10–11 mg/kg q8h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Aminophylline in dogs: IV, PO.
Cited course lengths for Aminophylline in dogs include: As needed; Chronic as needed; Chronic. Duration depends on the indication — match it to the specific dose rule in the table above.
Aminophylline is indicated in dogs for: Acute bronchospasm, Bronchodilation, chronic bronchitis, Collapsing trachea adjunct.
These are general warnings for Aminophylline across species; consult the dog dosing table above for species-specific guidance. Narrow therapeutic index. Monitor for tachycardia, GI upset, CNS stimulation, and seizures. Avoid concurrent fluoroquinolones (decreased metabolism). IV administration must be slow.
Why a species-specific page? Aminophylline pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.