Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Aminophylline is dosed at 5–10 mg/kg IV q8h in dogs, per Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.82 (2026-08-01).. Aminophylline is used in dogs for Acute bronchospasm, Bronchodilation, chronic bronchitis, Collapsing trachea adjunct. Routes documented in dogs: IV, PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 3 cited dose rules for Aminophylline in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 5–10 mg/kg | q8h | As needed | Acute bronchospasm | Moderate | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.82 (2026-08-01). |
| PO | 10–11 mg/kg | q8h | Chronic as needed | Bronchodilation, chronic bronchitis |
| Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 10–11 mg/kg | q8h | Chronic | Collapsing trachea adjunct | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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Phosphodiesterase inhibitor and adenosine receptor antagonist. Relaxes bronchial smooth muscle, stimulates respiratory drive, and has mild diuretic effect.
Narrow therapeutic index. Monitor for tachycardia, GI upset, CNS stimulation, and seizures. Avoid concurrent fluoroquinolones (decreased metabolism). IV administration must be slow.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Aminophylline dose ranges in dogs, with cited source references: IV 5–10 mg/kg q8h; PO 10–11 mg/kg q8h; PO 10–11 mg/kg q8h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Aminophylline in dogs: IV, PO.
Cited course lengths for Aminophylline in dogs include: As needed; Chronic as needed; Chronic. Duration depends on the indication — match it to the specific dose rule in the table above.
Aminophylline is indicated in dogs for: Acute bronchospasm, Bronchodilation, chronic bronchitis, Collapsing trachea adjunct.
These are general warnings for Aminophylline across species; consult the dog dosing table above for species-specific guidance. Narrow therapeutic index. Monitor for tachycardia, GI upset, CNS stimulation, and seizures. Avoid concurrent fluoroquinolones (decreased metabolism). IV administration must be slow.
Why a species-specific page? Aminophylline pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.