Question 1

What is Aminophylline used for?

Accepted Answer

Aminophylline is indicated for: Acute bronchospasm, Bronchodilation, chronic bronchitis, Collapsing trachea adjunct, Feline asthma (adjunct bronchodilator).

Question 2

What routes can Aminophylline be administered by?

Accepted Answer

Available routes: PO, IV, IM.

Question 3

Which species have cited Aminophylline dosing data?

Accepted Answer

Aminophylline dosing in the ExoticRx formulary covers 5 species: African Grey Parrot, Cat (Domestic), Dog (Domestic), Guinea Pig, Rabbit (Domestic).

Question 4

Is Aminophylline a controlled substance?

Accepted Answer

Aminophylline is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Aminophylline?

Accepted Answer

Narrow therapeutic index. Monitor for tachycardia, GI upset, CNS stimulation, and seizures. Avoid concurrent fluoroquinolones (decreased metabolism). IV administration must be slow.

Question 6

What are the side effects of Aminophylline?

Accepted Answer

Reported side effects, adverse reactions, and contraindications for Aminophylline: Narrow therapeutic index. Monitor for tachycardia, GI upset, CNS stimulation, and seizures. Avoid concurrent fluoroquinolones (decreased metabolism). IV administration must be slow.

Question 7

How does Aminophylline work?

Accepted Answer

Phosphodiesterase inhibitor and adenosine receptor antagonist. Relaxes bronchial smooth muscle, stimulates respiratory drive, and has mild diuretic effect.

Species	Route	Dose	Frequency	Evidence	Source
Cat (Domestic)	IV	5–6 mg/kg	q12h	Moderate	Plumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)	PO	5–6 mg/kg	q12h	Moderate	Plumb's Veterinary Drug Handbook, 9th Ed

Aminophylline

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Aminophylline dosing data (8 dose rules)

Evidence levels across 8 dose rules

Backed by 2 published sources

Sample dosing (2 of 8 cited rules)

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