ExoticRx · exoticrx.com/drugs/ambrisentan
US brand names:Letairis
Selective endothelin type A (ETA) receptor antagonist that blocks endothelin-1 mediated vasoconstriction and smooth muscle proliferation in pulmonary vasculature.
Hepatotoxicity risk — monitor liver enzymes. Peripheral edema. Teratogenic. Used for pulmonary hypertension in dogs when sildenafil alone is insufficient.
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.