Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Dextromethorphan is dosed at 1–2 mg/kg PO q6-8h in dogs, per Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.254 (2026-08-01).. Dextromethorphan is used in dogs for Mild cough suppression. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Dextromethorphan in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Robitussin DM
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 1–2 mg/kg | q6-8h | Short-term | Mild cough suppression | Weak | Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.254 (2026-08-01). |
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Suppresses cough reflex by acting on the cough center in the medulla. NMDA receptor antagonist at higher doses.
OTC availability. Limited efficacy in veterinary patients. Ensure product does not contain xylitol, acetaminophen, or pseudoephedrine. Serotonin syndrome risk with other serotonergic drugs.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Dextromethorphan dose range in dogs, with cited source references: PO 1–2 mg/kg q6-8h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Dextromethorphan in dogs: PO.
Cited course lengths for Dextromethorphan in dogs include: Short-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Dextromethorphan is indicated in dogs for: Mild cough suppression.
These are general warnings for Dextromethorphan across species; consult the dog dosing table above for species-specific guidance. OTC availability. Limited efficacy in veterinary patients. Ensure product does not contain xylitol, acetaminophen, or pseudoephedrine. Serotonin syndrome risk with other serotonergic drugs.
Why a species-specific page? Dextromethorphan pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.