Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Cyproheptadine is dosed at 0.3–2 mg/kg PO q8-12h in dogs, per Plumb's Veterinary Drug Handbook, 10th ed (2023) — Plumb's 10th ed printed p.327, Cyproheptadine monograph spanning p.327-328. Cyproheptadine is used in dogs for Allergic disease / appetite stimulation. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Cyproheptadine in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Periactin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.3–2 mg/kg | q8-12h | Variable; depends on indication | Allergic disease / appetite stimulation | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023) — Plumb's 10th ed printed p.327, Cyproheptadine monograph spanning p.327-328.Compilation only — we have not located an independent source that prints this figure. |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.1–0.5 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.120 | 0.1-0.5 mg/kg p.o. q8-12h. Cytarabine (Cytosine arabinoside, Ara-C) (Cytarabine*, Cytosar-U*) POM |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Piperidine antihistamine with potent 5-HT2A serotonin receptor antagonism and H1 blockade, providing both antiallergic and antiserotonergic effects. Also acts as bronchodilator.
Appetite stimulation is a prominent effect. Sedation possible. Used for feline asthma as bronchodilator adjunct and serotonin syndrome antidote.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Cyproheptadine dose range in dogs, with cited source references: PO 0.3–2 mg/kg q8-12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Cyproheptadine in dogs: PO.
Cited course lengths for Cyproheptadine in dogs include: Variable; depends on indication. Duration depends on the indication — match it to the specific dose rule in the table above.
Cyproheptadine is indicated in dogs for: Allergic disease / appetite stimulation.
These are general warnings for Cyproheptadine across species; consult the dog dosing table above for species-specific guidance. Appetite stimulation is a prominent effect. Sedation possible. Used for feline asthma as bronchodilator adjunct and serotonin syndrome antidote.
Why a species-specific page? Cyproheptadine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.