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Pentoxifylline (Respiratory) for Cat

Cat · Felis catus · typical adult weight 2.50–7.00 kg

Pentoxifylline (Respiratory) is used in cat for Pulmonary disease adjunct. Routes documented in cat: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Pentoxifylline (Respiratory) in cat, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Trental

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
PO10–25 mg/kgq8-12hLong-term; investigationalPulmonary disease adjunctWeakPlumb's Veterinary Drug Handbook, 9th Ed

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Mechanism of action

Non-selective phosphodiesterase inhibitor that improves red blood cell deformability, reduces blood viscosity, and inhibits TNF-alpha and neutrophil activation in pulmonary vasculature.

Side effects & warnings

GI upset at initiation. Used for pulmonary fibrosis and chronic bronchitis adjunct therapy. Anti-inflammatory effects complement bronchodilators.

Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Respiratory drugs with cat dosing

Pentoxifylline (Respiratory) dosing in other species

Why a species-specific page? Pentoxifylline (Respiratory) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.