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Doxapram for Guinea Pig

Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg

Doxapram is used in guinea pig for Post-anesthetic apnea. Routes documented in guinea pig: IV. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Doxapram in guinea pig, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Dopram

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
IV2–5 mg/kgonceSingle dosePost-anesthetic apneaExtrapolatedCarpenter's Exotic Animal Formulary, 6th Ed

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These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.

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Mechanism of action

Stimulates peripheral carotid chemoreceptors and central medullary respiratory centers, increasing tidal volume and respiratory rate.

Side effects & warnings

Short duration of action (minutes). Use for neonatal resuscitation or post-anesthetic apnea. May cause hypertension, tachycardia, and seizures at high doses. Ensure adequate airway before use.

Species-specific contraindications and adverse-reaction reports for guinea pig may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Respiratory drugs with guinea pig dosing

Doxapram dosing in other species

Why a species-specific page? Doxapram pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pig — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.