Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg
Theophylline is dosed at 4–10 mg/kg PO q8-12h in guinea pigs, per Fehr M, Sassenburg L, Zwart P. Krankheiten der Heimtiere, 8th ed., Schluetersche Verlagsgesellschaft, Hannover, Germany; 2015. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.802 (2026-08-01, PENDING REVIEW). Theophylline is used in guinea pigs for Bronchodilation. Routes documented in guinea pigs: PO. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Theophylline in guinea pigs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Theo-Dur, Theo-24
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 4–10 mg/kg | q8-12h | Bronchodilation | Moderate | Fehr M, Sassenburg L, Zwart P. Krankheiten der Heimtiere, 8th ed., Schluetersche Verlagsgesellschaft, Hannover, Germany; 2015. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.802 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits phosphodiesterase, increasing cAMP. Also antagonizes adenosine receptors. Relaxes bronchial smooth muscle and improves diaphragmatic contractility.
Narrow therapeutic index. Serum monitoring recommended (10-20 mcg/ml). Tachycardia, GI upset, CNS stimulation, seizures in overdose. Many drug interactions (fluoroquinolones, cimetidine increase levels).
Species-specific contraindications and adverse-reaction reports for guinea pigs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Theophylline dose range in guinea pigs, with cited source references: PO 4–10 mg/kg q8-12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Theophylline in guinea pigs: PO.
Theophylline is indicated in guinea pigs for: Bronchodilation.
These are general warnings for Theophylline across species; consult the guinea pig dosing table above for species-specific guidance. Narrow therapeutic index. Serum monitoring recommended (10-20 mcg/ml). Tachycardia, GI upset, CNS stimulation, seizures in overdose. Many drug interactions (fluoroquinolones, cimetidine increase levels).
Why a species-specific page? Theophylline pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pigs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.