Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Ursodiol Suspension is dosed at 10–15 mg/kg PO q24h in dogs, per Watson PJ. Chapter 142: Chronic Hepatitis Therapy. In: Bonagura JD, Twedt DC, eds. Current Veterinary Therapy XV. Elsevier Saunders; 2014:583-587. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1315 (2026-08-01). — Plumb's 10th ed (held) printed p.1288, Ursodiol monograph spanning p.1287-1288; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 — Plumb's Veterinary Drug Handbook, 10th ed (held), Ursodiol monograph, printed p.1288 (corpus PDF p.1315), DOGS: "Medical treatment of biliary sludge (microlithiasis) and adjunctive treatment of acute and chronic […]"; contraindication from the same monograph, printed p.1287 (corpus PDF p.1314): "It is also contraindicated in patients hypersensitive to it or other bile acid products and in […]" [INDICATION CORRECTED 2026-08-12, two readers.]. Ursodiol Suspension is used in dogs for Biliary sludge (microlithiasis); adjunctive treatment of acute/chronic NONOBSTRUCTIVE cholestatic disorders or chronic hepatitis — CONTRAINDICATED with complete extrahepatic bile duct obstruction. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Ursodiol Suspension in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Ursofalk Suspension
| Route | Dose | Frequency | Duration | Indication | Evidence |
|---|
| Source |
|---|
| PO | 10–15 mg/kg | q24h | Long-term; 3-6 months minimum trial | Biliary sludge (microlithiasis); adjunctive treatment of acute/chronic NONOBSTRUCTIVE cholestatic disorders or chronic hepatitis — CONTRAINDICATED with complete extrahepatic bile duct obstruction | Moderate | Watson PJ. Chapter 142: Chronic Hepatitis Therapy. In: Bonagura JD, Twedt DC, eds. Current Veterinary Therapy XV. Elsevier Saunders; 2014:583-587. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1315 (2026-08-01). — Plumb's 10th ed (held) printed p.1288, Ursodiol monograph spanning p.1287-1288; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 — Plumb's Veterinary Drug Handbook, 10th ed (held), Ursodiol monograph, printed p.1288 (corpus PDF p.1315), DOGS: "Medical treatment of biliary sludge (microlithiasis) and adjunctive treatment of acute and chronic […]"; contraindication from the same monograph, printed p.1287 (corpus PDF p.1314): "It is also contraindicated in patients hypersensitive to it or other bile acid products and in […]" [INDICATION CORRECTED 2026-08-12, two readers.] |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 10–15 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.858 | • 10-15 mg/kg q24h PO; animals with liver disease should receive 15 mg/kg. |
| 15 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.858 | • 10-15 mg/kg q24h PO; animals with liver disease should receive 15 mg/kg. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Hydrophilic bile acid that displaces hepatotoxic bile acids, provides cytoprotective and anti-inflammatory effects on hepatocytes and biliary epithelium.
Easier to dose small animals than capsule form. Contraindicated in complete biliary obstruction. Monitor liver enzymes.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Ursodiol Suspension dose range in dogs, with cited source references: PO 10–15 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Ursodiol Suspension in dogs: PO.
Cited course lengths for Ursodiol Suspension in dogs include: Long-term; 3-6 months minimum trial. Duration depends on the indication — match it to the specific dose rule in the table above.
Ursodiol Suspension is indicated in dogs for: Biliary sludge (microlithiasis); adjunctive treatment of acute/chronic NONOBSTRUCTIVE cholestatic disorders or chronic hepatitis — CONTRAINDICATED with complete extrahepatic bile duct obstruction.
These are general warnings for Ursodiol Suspension across species; consult the dog dosing table above for species-specific guidance. Easier to dose small animals than capsule form. Contraindicated in complete biliary obstruction. Monitor liver enzymes.
Why a species-specific page? Ursodiol Suspension pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.