Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Permethrin is dosed at Row as printed (p.145): BSAVA printed p.129, Dinotefuran (Vectra 3D) POM-V, Formulations: "Topical spot-on available in 5 sizes: 6.4 mg dinotefuran/kg, 0.6 mg pyriproxyfen/kg and 46.6 mg permethrin/kg" — DOSES: "Dogs: One spot-on monthly in dogs, per BSAVA Small Animal Formulary, 10th ed., Part A — Dinotefuran (Vectra 3D), DOSES, printed p.129 (corpus PDF p.145); and Imidacloprid (+permethrin, Advantix), DOSES, printed p.203 (corpus PDF p.219). Corroborated by Plumb's Veterinary Drug Handbook 9th ed., "Permethrin/Permethrin Combinations, Topical", printed p.1459 (corpus PDF p.1486).. Permethrin is used in dogs for Flea and tick prevention. Routes documented in dogs: Topical. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Permethrin in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Vectra 3D, K9 Advantix
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| Topical | Row as printed (p.145): BSAVA printed p.129, Dinotefuran (Vectra 3D) POM-V, Formulations: "Topical spot-on available in 5 sizes: 6.4 mg dinotefuran/kg, 0.6 mg pyriproxyfen/kg and 46.6 mg permethrin/kg" — DOSES: "Dogs: One spot-on monthly | q30 days | Monthly application | Flea and tick prevention | Strong | BSAVA Small Animal Formulary, 10th ed., Part A — Dinotefuran (Vectra 3D), DOSES, printed p.129 (corpus PDF p.145); and Imidacloprid (+permethrin, Advantix), DOSES, printed p.203 (corpus PDF p.219). Corroborated by Plumb's Veterinary Drug Handbook 9th ed., "Permethrin/Permethrin Combinations, Topical", printed p.1459 (corpus PDF p.1486). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Disrupts sodium channel function in arthropod nervous system causing paralysis. Repellent and insecticidal activity.
EXTREMELY TOXIC TO CATS — even small exposures can be fatal (tremors, seizures, death). Dogs only. Do not apply to dogs that co-habit with cats.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Permethrin dose range in dogs, with cited source references: Topical Row as printed (p.145): BSAVA printed p.129, Dinotefuran (Vectra 3D) POM-V, Formulations: "Topical spot-on available in 5 sizes: 6.4 mg dinotefuran/kg, 0.6 mg pyriproxyfen/kg and 46.6 mg permethrin/kg" — DOSES: "Dogs: One spot-on monthly q30 days. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Permethrin in dogs: Topical.
Cited course lengths for Permethrin in dogs include: Monthly application. Duration depends on the indication — match it to the specific dose rule in the table above.
Permethrin is indicated in dogs for: Flea and tick prevention.
These are general warnings for Permethrin across species; consult the dog dosing table above for species-specific guidance. EXTREMELY TOXIC TO CATS — even small exposures can be fatal (tremors, seizures, death). Dogs only. Do not apply to dogs that co-habit with cats.
Why a species-specific page? Permethrin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.