Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Propantheline is dosed at 0.25–0.5 mg/kg PO q8h in dogs, per Papich MG. Saunders Handbook of Veterinary Drugs, 4th ed. (2016), Propantheline Bromide, printed p.682 (corpus PDF p.710); corroborated by BSAVA Small Animal Formulary 10th ed., Propantheline, printed p.345 (corpus PDF p.361) — SOURCE EDITION: BSAVA Small Animal Formulary, Part A — Canine and Feline — ISBN 9781910443705, https://openlibrary.org/isbn/9781910443705; Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855. Propantheline is used in dogs for GI smooth-muscle spasm / hypermotility (antispasmodic-antisecretory). Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Propantheline in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Pro-Banthine
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.25–0.5 mg/kg | q8h | Short to medium-term; as needed | GI smooth-muscle spasm / hypermotility (antispasmodic-antisecretory) |
| Weak |
| Papich MG. Saunders Handbook of Veterinary Drugs, 4th ed. (2016), Propantheline Bromide, printed p.682 (corpus PDF p.710); corroborated by BSAVA Small Animal Formulary 10th ed., Propantheline, printed p.345 (corpus PDF p.361) — SOURCE EDITION: BSAVA Small Animal Formulary, Part A — Canine and Feline — ISBN 9781910443705, https://openlibrary.org/isbn/9781910443705; Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.25–0.5 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.361 | 0.25-0.5 mg/kg p.o. q8-12h. |
| 0.2 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.361 | 0.2 mg/kg p.o. q6-8h. |
| 0.25 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.361 | 0.25 mg/kg p.o. q8-12h (round dose to nearest 3.75 mg). |
| 0.25–0.5 |
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Quaternary ammonium antimuscarinic that inhibits GI smooth muscle contraction and reduces gastric acid secretion by blocking muscarinic M1/M3 receptors.
Anticholinergic effects: dry mouth, constipation, urinary retention, mydriasis. Contraindicated in GI obstruction or glaucoma.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Propantheline dose range in dogs, with cited source references: PO 0.25–0.5 mg/kg q8h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Propantheline in dogs: PO.
Cited course lengths for Propantheline in dogs include: Short to medium-term; as needed. Duration depends on the indication — match it to the specific dose rule in the table above.
Propantheline is indicated in dogs for: GI smooth-muscle spasm / hypermotility (antispasmodic-antisecretory).
These are general warnings for Propantheline across species; consult the dog dosing table above for species-specific guidance. Anticholinergic effects: dry mouth, constipation, urinary retention, mydriasis. Contraindicated in GI obstruction or glaucoma.
Why a species-specific page? Propantheline pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| PO |
| Papich Saunders Handbook of Veterinary Drugs, 4th edp.710 |
| • 0.25-0.5 mg/kg q8-12h PO. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.