ExoticRx · exoticrx.com/drugs/propantheline
US brand names:Pro-Banthine
Propantheline is dosed at 0.25–0.5 mg/kg PO q8h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Quaternary ammonium antimuscarinic that inhibits GI smooth muscle contraction and reduces gastric acid secretion by blocking muscarinic M1/M3 receptors.
Anticholinergic effects: dry mouth, constipation, urinary retention, mydriasis. Contraindicated in GI obstruction or glaucoma.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.