Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Febantel is dosed at 10–25 mg/kg PO q24h x 3 days in dogs, per Montoya A, Dado D, Mateo M, Espinosa C, Miro G. Efficacy of Drontal Flavour Plus (50 mg praziquantel, 144 mg pyrantel embonate, 150 mg febantel per tablet) against Giardia sp in naturally infected dogs. Parasitol Res. 2008;103(5):1141-1144. doi:10.1007/s00436-008-1107-0 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1120 (2026-08-01). — LOCATOR CONVENTION 2026-08-07: the bare 'p.1120' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.1093; verified by finding the drug named there. If you are holding the book, turn to p.1093. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Febantel is used in dogs for GI nematodes and Giardia. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Febantel in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Rintal
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 10–25 mg/kg | q24h x 3 days | 3 days (as Drontal Plus) | GI nematodes and Giardia | Strong | Montoya A, Dado D, Mateo M, Espinosa C, Miro G. Efficacy of Drontal Flavour Plus (50 mg praziquantel, 144 mg pyrantel embonate, 150 mg febantel per tablet) against Giardia sp in naturally infected dogs. Parasitol Res. 2008;103(5):1141-1144. doi:10.1007/s00436-008-1107-0 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1120 (2026-08-01). — LOCATOR CONVENTION 2026-08-07: the bare 'p.1120' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.1093; verified by finding the drug named there. If you are holding the book, turn to p.1093. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 10 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.341 | • 10 mg/kg febantel alone or in combination with 1 mg/kg praziquantel PO with |
| 1 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.341 | • 10 mg/kg febantel alone or in combination with 1 mg/kg praziquantel PO with |
| 15 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.341 | • Puppies: 15 mg/kg febantel alone or in combination with 1.5 mg/kg praziquantel |
| 1.5 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.341 | • Puppies: 15 mg/kg febantel alone or in combination with 1.5 mg/kg praziquantel |
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Prodrug metabolized to fenbendazole and oxfendazole. Inhibits microtubule formation in nematodes by binding beta-tubulin.
Often combined with pyrantel and praziquantel (Drontal Plus). Safe in dogs. Not recommended in cats. Teratogenic in some species.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Febantel dose range in dogs, with cited source references: PO 10–25 mg/kg q24h x 3 days. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Febantel in dogs: PO.
Cited course lengths for Febantel in dogs include: 3 days (as Drontal Plus). Duration depends on the indication — match it to the specific dose rule in the table above.
Febantel is indicated in dogs for: GI nematodes and Giardia.
These are general warnings for Febantel across species; consult the dog dosing table above for species-specific guidance. Often combined with pyrantel and praziquantel (Drontal Plus). Safe in dogs. Not recommended in cats. Teratogenic in some species.
Why a species-specific page? Febantel pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 27–35 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.341 | • For treatment of Giardia, it has been combined with pyrantel (27-35 mg/kg |
| 27–35 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.341 | febantel 1 27-35 mg/kg pyrantel) q24h PO for 3 days. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.