Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Imidacloprid-Moxidectin Topical is used in dogs for Fleas, heartworm, intestinal parasites. Routes documented in dogs: TOPICAL. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Imidacloprid-Moxidectin Topical in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Advantage Multi
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| TOPICAL | Monthly topical | q30 days | Monthly, year-round | Fleas, heartworm, intestinal parasites | Strong | ADVANTAGE MULTI FOR DOGS - Imidacloprid, Moxidectin Solution [US Product Label for Dogs]. Elanco US, Inc.; 2021. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3fc1a42b-6576-4890-aa0c-5c0eb903c85a — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.942 (2026-08-01). |
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Enter your dog's weight to check these cited ranges in the calculator — unit and concentration math done for you.
Imidacloprid (neonicotinoid) disrupts nicotinic acetylcholine transmission in fleas; moxidectin targets glutamate-gated chloride channels in nematodes. Heartworm prevention plus flea control.
Available for dogs and cats. Monthly topical. Do not allow ingestion. Keep treated animals separated until dry. Not for rabbits (ferrets have specific formulation).
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Imidacloprid-Moxidectin Topical dose range in dogs, with cited source references: TOPICAL Monthly topical q30 days. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Imidacloprid-Moxidectin Topical in dogs: TOPICAL.
Cited course lengths for Imidacloprid-Moxidectin Topical in dogs include: Monthly, year-round. Duration depends on the indication — match it to the specific dose rule in the table above.
Imidacloprid-Moxidectin Topical is indicated in dogs for: Fleas, heartworm, intestinal parasites.
These are general warnings for Imidacloprid-Moxidectin Topical across species; consult the dog dosing table above for species-specific guidance. Available for dogs and cats. Monthly topical. Do not allow ingestion. Keep treated animals separated until dry. Not for rabbits (ferrets have specific formulation).
Why a species-specific page? Imidacloprid-Moxidectin Topical pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.