Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Calcium Gluconate is dosed at 50–150 mg/kg IV PRN in dogs, per Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.202 (2026-08-01). — Plumb's 10th ed (held) printed p.174-176 (corpus PDF p.201-203), Calcium, IV (-Borogluconate, -Chloride, -Gluconate) monograph, Dosages [LOCATOR CORRECTED 2026-08-12 — the clause previously here named the Calcium Acetate monograph, an oral phosphate binder]; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Calcium Gluconate is used in dogs for Black widow spider envenomation, Hypocalcemia, eclampsia, hyperkalemia (cardioprotection), Ethylene glycol toxicity (hyperkalemia), Post-eclampsia maintenance. Routes documented in dogs: IV, PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 4 cited dose rules for Calcium Gluconate in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 50–150 mg/kg | PRN | As needed for muscle rigidity | Black widow spider envenomation | Moderate | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.202 (2026-08-01). — Plumb's 10th ed (held) printed p.174-176 (corpus PDF p.201-203), Calcium, IV (-Borogluconate, -Chloride, -Gluconate) monograph, Dosages [LOCATOR CORRECTED 2026-08-12 — the clause previously here named the Calcium Acetate monograph, an oral phosphate binder]; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| IV | 50–150 mg/kg | once | Slow IV over 10-20 min with ECG monitoring | Hypocalcemia, eclampsia, hyperkalemia (cardioprotection) | Strong | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.202 (2026-08-01). — Plumb's 10th ed (held) printed p.174-176 (corpus PDF p.201-203), Calcium, IV (-Borogluconate, -Chloride, -Gluconate) monograph, Dosages [LOCATOR CORRECTED 2026-08-12 — the clause previously here named the Calcium Acetate monograph, an oral phosphate binder]; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| IV | 50–100 mg/kg | once | Slow IV with ECG monitoring | Ethylene glycol toxicity (hyperkalemia) | Strong | Polzin DJ, Osborne CA. Diseases of the Urinary Tract. In: Davis LE, ed. Handbook of Small Animal Therapeutics. New York: Churchill Livingstone; 1985:333-395. PMID: 42536520 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.202 (2026-08-01). — Plumb's 10th ed (held) printed p.174-176 (corpus PDF p.201-203), Calcium, IV (-Borogluconate, -Chloride, -Gluconate) monograph, Dosages [LOCATOR CORRECTED 2026-08-12 — the clause previously here named the Calcium Acetate monograph, an oral phosphate binder]; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| PO | 50–75 mg/kg | q8h | During lactation | Post-eclampsia maintenance | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.177-178 (corpus PDF p.204-205), Calcium, Oral (-Carbonate, -Gluconate, -Lactate) monograph, Dosages [LOCATOR CORRECTED 2026-08-12 — the clause previously here named the Calcium Acetate monograph, whose only printed figures are 60-90 and 30-60 mg/kg/day as a phosphate binder]; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Provides ionized calcium for neuromuscular function, cardiac conduction, and bone metabolism. Cardioprotective against hyperkalemia.
IV administration must be SLOW with ECG monitoring (cardiac arrest risk). Tissue necrosis if given SC undiluted at high concentrations. Dilute for SC use. Monitor ionized calcium levels.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Calcium Gluconate dose ranges in dogs, with cited source references: IV 50–150 mg/kg PRN; IV 50–150 mg/kg once; IV 50–100 mg/kg once; PO 50–75 mg/kg q8h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Calcium Gluconate in dogs: IV, PO.
Cited course lengths for Calcium Gluconate in dogs include: As needed for muscle rigidity; Slow IV over 10-20 min with ECG monitoring; Slow IV with ECG monitoring; During lactation. Duration depends on the indication — match it to the specific dose rule in the table above.
Calcium Gluconate is indicated in dogs for: Black widow spider envenomation, Hypocalcemia, eclampsia, hyperkalemia (cardioprotection), Ethylene glycol toxicity (hyperkalemia), Post-eclampsia maintenance.
These are general warnings for Calcium Gluconate across species; consult the dog dosing table above for species-specific guidance. IV administration must be SLOW with ECG monitoring (cardiac arrest risk). Tissue necrosis if given SC undiluted at high concentrations. Dilute for SC use. Monitor ionized calcium levels.
Why a species-specific page? Calcium Gluconate pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.