Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Aminocaproic Acid is dosed at 500 mg per dog (NOT mg/kg) PO q8h in dogs, per Marin LM, Iazbik MC, Zaldivar-Lopez S, et al. Retrospective evaluation of the effectiveness of epsilon aminocaproic acid for the prevention of postamputation bleeding in retired racing Greyhounds with appendicular bone tumors: 46 cases (2003-2008). J Vet Emerg Crit Care (San Antonio). 2012;22(3):332-340. doi:10.1111/j.1476-4431.2012.00735.x — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.79 (2026-08-01). — Plumb's 10th ed (held) printed p.51, Aminocaproic Acid monograph spanning p.51-52; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 BASIS CORRECTED 2026-08-13: served as mg/kg, which the calculator multiplies by body weight. Plumb's Veterinary Drug Handbook 10th ed, corpus p.40, verbatim: "Used in conjunction with aminocaproic acid at a dosage of 500 mg per dog (NOT mg/kg) PO every 8 hours indefinitely." As a per-kg figure the served range delivered roughly 75-200 mg to a 5 kg dog and 750-2000 mg to a 50 kg dog against a printed flat 500 mg. Read from the page 2026-08-13.. Aminocaproic Acid is used in dogs for Degenerative myelopathy, post-surgical bleeding. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Aminocaproic Acid in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Amicar
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 500 mg per dog (NOT mg/kg) | q8h | Long-term for DM | Degenerative myelopathy, post-surgical bleeding | Weak | Marin LM, Iazbik MC, Zaldivar-Lopez S, et al. Retrospective evaluation of the effectiveness of epsilon aminocaproic acid for the prevention of postamputation bleeding in retired racing Greyhounds with appendicular bone tumors: 46 cases (2003-2008). J Vet Emerg Crit Care (San Antonio). 2012;22(3):332-340. doi:10.1111/j.1476-4431.2012.00735.x — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.79 (2026-08-01). — Plumb's 10th ed (held) printed p.51, Aminocaproic Acid monograph spanning p.51-52; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 BASIS CORRECTED 2026-08-13: served as mg/kg, which the calculator multiplies by body weight. Plumb's Veterinary Drug Handbook 10th ed, corpus p.40, verbatim: "Used in conjunction with aminocaproic acid at a dosage of 500 mg per dog (NOT mg/kg) PO every 8 hours indefinitely." As a per-kg figure the served range delivered roughly 75-200 mg to a 5 kg dog and 750-2000 mg to a 50 kg dog against a printed flat 500 mg. Read from the page 2026-08-13. |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits fibrinolysis by blocking plasminogen activator and, to a lesser extent, antiplasmin activity. Stabilizes clots.
Used for degenerative myelopathy (German Shepherds — controversial efficacy), post-surgical hemorrhage. Thrombosis risk. GI upset. Monitor for signs of thromboembolism.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Aminocaproic Acid dose range in dogs, with cited source references: PO 500 mg per dog (NOT mg/kg) q8h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Aminocaproic Acid in dogs: PO.
Cited course lengths for Aminocaproic Acid in dogs include: Long-term for DM. Duration depends on the indication — match it to the specific dose rule in the table above.
Aminocaproic Acid is indicated in dogs for: Degenerative myelopathy, post-surgical bleeding.
These are general warnings for Aminocaproic Acid across species; consult the dog dosing table above for species-specific guidance. Used for degenerative myelopathy (German Shepherds — controversial efficacy), post-surgical hemorrhage. Thrombosis risk. GI upset. Monitor for signs of thromboembolism.
Why a species-specific page? Aminocaproic Acid pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.