Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Hypertonic Saline is dosed at 4–5 ml/kg of 7.5% IV IV over 5-10 min in dogs, per Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.661 (2026-08-01).. Hypertonic Saline is used in dogs for Acute hemorrhagic shock, raised ICP. Routes documented in dogs: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Hypertonic Saline in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: 7.2% NaCl, 7.5% NaCl
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 4–5 ml/kg of 7.5% | IV over 5-10 min | Single bolus | Acute hemorrhagic shock, raised ICP | Moderate | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.661 (2026-08-01). |
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Osmotically draws intracellular and interstitial water into intravascular space. Rapid small-volume resuscitation. Reduces intracranial pressure.
Small volume resuscitation (4-5ml/kg IV over 5-10 min). Follow with isotonic crystalloids. Contraindicated in dehydration (no interstitial fluid to recruit). Monitor sodium and osmolality.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Hypertonic Saline dose range in dogs, with cited source references: IV 4–5 ml/kg of 7.5% IV over 5-10 min. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Hypertonic Saline in dogs: IV.
Cited course lengths for Hypertonic Saline in dogs include: Single bolus. Duration depends on the indication — match it to the specific dose rule in the table above.
Hypertonic Saline is indicated in dogs for: Acute hemorrhagic shock, raised ICP.
These are general warnings for Hypertonic Saline across species; consult the dog dosing table above for species-specific guidance. Small volume resuscitation (4-5ml/kg IV over 5-10 min). Follow with isotonic crystalloids. Contraindicated in dehydration (no interstitial fluid to recruit). Monitor sodium and osmolality.
Why a species-specific page? Hypertonic Saline pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.