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Hypertonic Saline for Dog

Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg

Hypertonic Saline is used in dog for Acute hemorrhagic shock, raised ICP. Routes documented in dog: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Hypertonic Saline in dog, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: 7.2% NaCl, 7.5% NaCl

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
IV4–5 ml/kg of 7.5%IV over 5-10 minSingle bolusAcute hemorrhagic shock, raised ICPModeratePlumb's Veterinary Drug Handbook, 9th Ed

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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.

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Mechanism of action

Osmotically draws intracellular and interstitial water into intravascular space. Rapid small-volume resuscitation. Reduces intracranial pressure.

Side effects & warnings

Small volume resuscitation (4-5ml/kg IV over 5-10 min). Follow with isotonic crystalloids. Contraindicated in dehydration (no interstitial fluid to recruit). Monitor sodium and osmolality.

Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Emergency drugs with dog dosing

Why a species-specific page? Hypertonic Saline pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.