Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Ammonium Chloride is dosed at 100 mg/kg PO q12h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed, Ammonium Chloride, printed p.66 (corpus plumb p.93); corroborated by Papich, Saunders Handbook of Veterinary Drugs, 5th Ed, p.37 (corpus papich p.65): 'Dogs: 100 mg/kg q12h PO'. Ammonium Chloride is used in dogs for Struvite dissolution (urinary acidification). Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Ammonium Chloride in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 100 mg/kg | q12h | Until struvites dissolved | Struvite dissolution (urinary acidification) | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed, Ammonium Chloride, printed p.66 (corpus plumb p.93); corroborated by Papich, Saunders Handbook of Veterinary Drugs, 5th Ed, p.37 (corpus papich p.65): 'Dogs: 100 mg/kg q12h PO' |
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Metabolized by liver releasing HCl and producing systemic acidification. Excreted renally as acidifying ammonium ion.
Used for metabolic alkalosis and struvite urolith prevention/dissolution. Contraindicated in hepatic insufficiency (ammonia cannot be metabolized). Monitor blood pH and electrolytes.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Ammonium Chloride dose range in dogs, with cited source references: PO 100 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Ammonium Chloride in dogs: PO.
Cited course lengths for Ammonium Chloride in dogs include: Until struvites dissolved. Duration depends on the indication — match it to the specific dose rule in the table above.
Ammonium Chloride is indicated in dogs for: Struvite dissolution (urinary acidification).
These are general warnings for Ammonium Chloride across species; consult the dog dosing table above for species-specific guidance. Used for metabolic alkalosis and struvite urolith prevention/dissolution. Contraindicated in hepatic insufficiency (ammonia cannot be metabolized). Monitor blood pH and electrolytes.
Why a species-specific page? Ammonium Chloride pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.