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Ammonium Chloride for Dog

Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg

Ammonium Chloride is used in dog for Struvite dissolution (urinary acidification). Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Ammonium Chloride in dog, drawn from published veterinary references. Verify against current literature before clinical use.

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
PO100–200 mg/kgq12hUntil struvites dissolvedStruvite dissolution (urinary acidification)ModeratePlumb's Veterinary Drug Handbook, 9th Ed

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Mechanism of action

Metabolized by liver releasing HCl and producing systemic acidification. Excreted renally as acidifying ammonium ion.

Side effects & warnings

Used for metabolic alkalosis and struvite urolith prevention/dissolution. Contraindicated in hepatic insufficiency (ammonia cannot be metabolized). Monitor blood pH and electrolytes.

Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Emergency drugs with dog dosing

Ammonium Chloride dosing in other species

Why a species-specific page? Ammonium Chloride pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.