Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Epinephrine is used in dog for Anaphylaxis, Cardiac arrest (IO route), Cardiac arrest (when IV not available), Cardiac arrest, anaphylaxis. Routes documented in dog: IM, IO, IT, IV, SC. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 6 cited dose rules for Epinephrine in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Adrenalin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 0.01–0.02 mg/kg | q5-15min | As needed for anaphylaxis | Anaphylaxis | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| IO | 0.01–0.02 mg/kg | q3-5min | During CPR | Cardiac arrest (IO route) | Moderate | RECOVER CPR Guidelines |
| IT | 0.02–0.1 mg/kg | q3-5min | During CPR | Cardiac arrest (when IV not available) | Moderate | RECOVER CPR Guidelines |
| IV | 0.01–0.02 mg/kg | q3-5min | During CPR/anaphylaxis | Cardiac arrest, anaphylaxis | Strong | RECOVER CPR Guidelines; Plumb's 9th Ed |
| IV | 0.01–0.05 mg/kg | q5-15min | Until hemodynamically stable | Anaphylactic shock (severe) | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| SC | 0.01–0.02 mg/kg | q15-20min | As needed | Vaccine reaction, urticaria | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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Non-selective adrenergic agonist (alpha and beta). Increases heart rate, contractility, and vascular tone. Bronchodilator. First-line for cardiac arrest and anaphylaxis.
Causes tachycardia, arrhythmias, hypertension. Dilute for IV use (1:10,000). Tissue necrosis if extravasated. Very short duration of action. Light-sensitive.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Epinephrine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.