Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Magnesium Sulfate is dosed at 0.15–0.3 mEq/kg IV Slow IV over 5-15 min (arrhythmia) or 10-20 min in dogs, per Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.819 (2026-08-01). — Plumb's 10th ed (held) printed p.791-792 (corpus PDF p.818-819), Magnesium, IV monograph, Dosages [LOCATOR CORRECTED 2026-08-12 — the clause previously here named the Magnesium Hydroxide monograph, an oral antacid]; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Magnesium Sulfate is used in dogs for Torsades de pointes, hypomagnesemia. Routes documented in dogs: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Magnesium Sulfate in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: MgSO4, Epsom Salt
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.15–0.3 mEq/kg | Slow IV over 5-15 min (arrhythmia) or 10-20 min | Until arrhythmia controlled | Torsades de pointes, hypomagnesemia | Moderate | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.819 (2026-08-01). — Plumb's 10th ed (held) printed p.791-792 (corpus PDF p.818-819), Magnesium, IV monograph, Dosages [LOCATOR CORRECTED 2026-08-12 — the clause previously here named the Magnesium Hydroxide monograph, an oral antacid]; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (meq/kg) | Route | Source | As printed |
|---|---|---|---|
| 1–2 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.497 | • 1-2 mEq/kg/day PO, equivalent to 0.5-1.0 mmol/kg PO (or 8-25 g/dog q24h PO). |
| 0.2–0.3 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.497 | • Intravenous dose for magnesium deficiency or arrhythmias: 0.2-0.3 mEq/kg |
| 0.12 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.497 | (0.1-0.15 mmol/kg) IV at a rate of 0.12 mEq/kg/min (0.06 mmol/kg/min). |
| 0.2–1 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.497 | 0.2-1.0 mEq/kg/day IV (0.1-0.5 mmol/kg/day). |
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Essential electrolyte. Blocks neuromuscular transmission, stabilizes cardiac membranes, and causes smooth muscle relaxation. Cofactor for 300+ enzymes.
Treatment for hypomagnesemia, torsades de pointes, and eclampsia. Slow IV infusion. Respiratory depression at high levels. Monitor ECG and reflexes. Antidote: calcium gluconate.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Magnesium Sulfate dose range in dogs, with cited source references: IV 0.15–0.3 mEq/kg Slow IV over 5-15 min (arrhythmia) or 10-20 min. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Magnesium Sulfate in dogs: IV.
Cited course lengths for Magnesium Sulfate in dogs include: Until arrhythmia controlled. Duration depends on the indication — match it to the specific dose rule in the table above.
Magnesium Sulfate is indicated in dogs for: Torsades de pointes, hypomagnesemia.
These are general warnings for Magnesium Sulfate across species; consult the dog dosing table above for species-specific guidance. Treatment for hypomagnesemia, torsades de pointes, and eclampsia. Slow IV infusion. Respiratory depression at high levels. Monitor ECG and reflexes. Antidote: calcium gluconate.
Why a species-specific page? Magnesium Sulfate pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 0.75–1 |
| — |
| Papich Saunders Handbook of Veterinary Drugs, 4th edp.497 |
| • Use during fluid therapy: Supplement fluid solutions with 0.75-1 mEq/kg/day. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.