ExoticRx · exoticrx.com/drugs/magnesium-sulfate
US brand names:MgSO4, Epsom Salt(injectable)
Magnesium Sulfate is dosed at 0.15–0.3 mEq/kg IV CRI over 24h in cats, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Essential electrolyte. Blocks neuromuscular transmission, stabilizes cardiac membranes, and causes smooth muscle relaxation. Cofactor for 300+ enzymes.
Treatment for hypomagnesemia, torsades de pointes, and eclampsia. Slow IV infusion. Respiratory depression at high levels. Monitor ECG and reflexes. Antidote: calcium gluconate.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Magnesium Sulfate CRI dose rules from the ExoticRx formulary. Verify against current literature before clinical use; CRI rates differ from bolus dosing and route, dilution, and monitoring matter. Sign in for the complete per-species CRI protocol set.
| Species | Route | Rate | Indication | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | IV | 0.15–0.3 mEq/kgCRI over 24h | Hypomagnesemia, refractory seizures | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| Dog (Domestic) | IV | 0.15–0.3 mEq/kgIV CRI over 15-60 min | Torsades de pointes, hypomagnesemia | Moderate | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.819 (2026-08-01). |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.
Hypomagnesemia, refractory seizures
Torsades de pointes, hypomagnesemia