ExoticRx · exoticrx.com/drugs/magnesium-sulfate-injectable
US brand names:MgSO4
Magnesium Sulfate Injectable is dosed at 0.15–0.3 mEq/kg IV CRI over 12-24 hours in cats, per Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.791-792 (corpus PDF p.818-819), Magnesium, IV monograph, Dosages [LOCATOR CORRECTED 2026-08-12 — the clause previously here named the Magnesium Hydroxide monograph, an oral antacid]; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — figure located 2026-08-05 at Plumb's 10th ed printed p.792, Magnesium, IV monograph; the page cited previously does not carry it. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Verify against current literature before clinical use.
Essential cofactor for >300 enzymatic reactions. Membrane stabilizer, smooth muscle relaxant, and NMDA receptor antagonist.
Rapid IV push can cause hypotension, bradycardia, respiratory depression. Monitor reflexes and respiratory rate. Reduce dose in renal impairment.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Magnesium Sulfate Injectable CRI dose rules from the ExoticRx formulary. Verify against current literature before clinical use; CRI rates differ from bolus dosing and route, dilution, and monitoring matter. Sign in for the complete per-species CRI protocol set.
| Species | Route | Rate | Indication | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | IV | 0.15–0.3 mEq/kgCRI over 12-24 hours | Hypomagnesemia, refractory arrhythmias | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.791-792 (corpus PDF p.818-819), Magnesium, IV monograph, Dosages [LOCATOR CORRECTED 2026-08-12 — the clause previously here named the Magnesium Hydroxide monograph, an oral antacid]; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — figure located 2026-08-05 at Plumb's 10th ed printed p.792, Magnesium, IV monograph; the page cited previously does not carry it. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| Dog (Domestic) | IV | 0.15–0.3 mEq/kgIV slowly over 10-20 min, then CRI over 12-24 h | Hypomagnesemia, refractory ventricular arrhythmias |
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | IV | 0.15–0.3 mEq/kg | CRI over 12-24 hours | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.791-792 (corpus PDF p.818-819), Magnesium, IV monograph, Dosages [LOCATOR CORRECTED 2026-08-12 — the clause previously here named the Magnesium Hydroxide monograph, an oral antacid]; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — figure located 2026-08-05 at Plumb's 10th ed printed p.792, Magnesium, IV monograph; the page cited previously does not carry it. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| Dog (Domestic) | IV | 0.15–0.3 mEq/kg | IV slowly over 10-20 min, then CRI over 12-24 h | Moderate |
Upgrade to Pro or Student to unlock the full dose ranges and frequency for every species. The drug's mechanism, warnings, indications, and cited sources are free to read.
View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.
| Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.791-792 (corpus PDF p.818-819), Magnesium, IV monograph, Dosages [LOCATOR CORRECTED 2026-08-12 — the clause previously here named the Magnesium Hydroxide monograph, an oral antacid]; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — figure located 2026-08-05 at Plumb's 10th ed printed p.792, Magnesium, IV monograph; the page cited previously does not carry it. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Hypomagnesemia, refractory arrhythmias
Hypomagnesemia, refractory ventricular arrhythmias