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Aminocaproic Acid Oral

Amicar

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Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Emergency

Routes

POIV

Indications

Antifibrinolytic hemostasisbleeding disordersDegenerative myelopathy

Mechanism of Action

Competitively inhibits plasminogen activation, preventing fibrinolysis. Stabilizes existing clots by blocking conversion of plasminogen to plasmin.

Side effects & warnings

May cause GI upset. Contraindicated with DIC. Monitor for thrombosis. Used in dogs for degenerative myelopathy (off-label) and bleeding disorders.

Species with Aminocaproic Acid Oral dosing data (2 dose rules)

Cat (Domestic)Dog (Domestic)

Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs

Evidence levels across 2 dose rules

Weak×1Extrapolated×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published source

  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (2 of 2 cited rules)

A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

SpeciesRouteDoseFrequencyEvidenceSource
Cat (Domestic)PO50–100 mg/kgq6-8h IV or POExtrapolatedPlumb's Veterinary Drug Handbook, 9th Ed
Dog (Domestic)PO15–40 mg/kgq8hWeakPlumb's Veterinary Drug Handbook, 9th Ed

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