Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.
Calcium Gluconate is dosed at 50–100 mg/kg IV once in rabbits, per Carpenter's Exotic Animal Formulary, 6th Ed — Carpenter's Exotic Animal Formulary, 6th ed, Table 10.1. NOTE: the served figure was matched against the table as a whole, not against this drug's own row, so confirm the number on the page before relying on it. Verify against current literature before clinical use.
Provides ionized calcium for neuromuscular function, cardiac conduction, and bone metabolism. Cardioprotective against hyperkalemia.
Side effects & warnings
IV administration must be SLOW with ECG monitoring (cardiac arrest risk). Tissue necrosis if given SC undiluted at high concentrations. Dilute for SC use. Monitor ionized calcium levels.
Species with Calcium Gluconate dosing data (35 dose rules)
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Sample dosing (2 of 35 cited rules)
A dog/cat sample is shown here. Cited dosing for all 24 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
Plumb's 10th ed printed p.174-176, Calcium, IV (-Borogluconate, -Chloride, -Gluconate) monograph, Dosages.Compilation only — we have not located an independent source that prints this figure.
Polzin DJ, Osborne CA. Diseases of the Urinary Tract. In: Davis LE, ed. Handbook of Small Animal Therapeutics. New York: Churchill Livingstone; 1985:333-395. PMID: 42536520 — Plumb's 10th ed printed p.174-176, Calcium, IV (-Borogluconate, -Chloride, -Gluconate) monograph, Dosages.
· 208. Mans C, Braun J. Update on common nutritional disorders of captive reptiles. Vet Clin North Am Exot Anim Pract. 2014;17:369-395. — Source: Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1416
· 296. Mans C, Braun J. Update on common nutritional disorders of captive reptiles. Vet Clin North Am Exot Anim Pract. 2014;17:369-395. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.263 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.9 (Nutritional/Mineral/Fluid Support Used in Reptiles.a).
· 32. Bennett RA. Management of common reptile emergencies. Proc Annu Conf Assoc Rept Amph Vet; 1998:67-72. || 316. McArthur SDJ, Wilkinson RJ, Barrows MG. Tortoises and turtles. In: Meredith A, Redrobe S, eds. BSAVA Manual of Exotic Pets, 4th ed., British Small Animal Veterinary Association, Gloucestershire, GB; 2002:208-222. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.249 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.9 (Nutritional/Mineral/Fluid Support Used in Reptiles.a).
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39. Lennox AM. Emergency and critical care procedures in sugar gliders (Petaurus breviceps), African hedgehogs (Atelerix albiventris), and prairie dogs (Cynomys spp). Vet Clin North Am Exot Anim Pract. 2007;10:533-555. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.744 — Carpenter's Exotic Animal Formulary 6th ed, Table 8.7 (Miscellaneous Agents Used in Hedgehogs).
· 420. Huckabee JR. Raptor therapeutics. Vet Clin North Am Exot Anim Pract. 2000;3:91-116. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.475 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.11 (Nutritional/Mineral Support and Supplementation Used in Birds).
· 423. Huff DG. Avian fluid therapy and nutritional therapeutics. Semin Avian Exot Pet Med. 1993;2:13-16. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.475 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.11 (Nutritional/Mineral Support and Supplementation Used in Birds).
· 43. Bailey TA, Apo MM. Pharmaceutics commonly used in avian medicine. In: Samour J, eds. Avian Medicine, 3rd ed., Mosby Elsevier, Edinburgh, Scotland; 2016:637-678. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.475 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.11 (Nutritional/Mineral Support and Supplementation Used in Birds).
· 45. Lightfoot T. Therapeutics of African pygmy hedgehogs and prairie dogs. Vet Clin North Am Exot Anim Pract. 2000;3:155-172. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.744 doi:10.1016/s1094-9194(17)30099-3 — Carpenter's Exotic Animal Formulary 6th ed, Table 8.7 (Miscellaneous Agents Used in Hedgehogs).
· 891. Stanford M. Clinical pathology of hypocalcaemia in adult grey parrots (Psittacus erithacus). Vet Rec. 2007;161:456-457. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.475 doi:10.1136/vr.161.13.456 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.11 (Nutritional/Mineral Support and Supplementation Used in Birds).
· BSAVA Small Animal Formulary, 10th ed., Part A: Canine and Feline, Calcium salts, printed p.60 — cats, parenteral hypocalcaemia 95-140 mg calcium gluconate/kg slow IV, then 2.5 ml/kg of 10% calcium gluconate q6-8h — plus Plumb's 10th ed. printed p.175, which prints our exact volume (0.5-1 mL/kg of calcium gluconate 10% = 50-100 mg/kg of the gluconate salt).
· Bennett RA. Management of common reptile emergencies. Proc Annu Conf Assoc Rept Amph Vet; 1998:67-72. (co-cited: McArthur SDJ, Wilkinson RJ, Barrows MG. Tortoises and turtles. In: Meredith A, Redrobe S, eds. BSAVA Manual of Exotic Pets, 4th ed., British Small Animal Veterinary Association, Gloucestershire, GB; 2002:208-222.) — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.249 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.9 (Nutritional/Mineral/Fluid Support Used in Reptiles.a).
· Bennett RA. Management of common reptile emergencies. Proc Annu Conf Assoc Rept Amph Vet; 1998:67-72. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.263 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.9 (Nutritional/Mineral/Fluid Support Used in Reptiles.a).
· BennettRA. Management of common reptile emergencies. Proc Annu Conf Assoc Rept Amph Vet; 1998:67-72. | McArthur SD.J, Wilkinson RJ, Barrows MG. Tortoises and turtles. In: Meredith A, Redrobe S, eds. BSAVA Manual of Exotic Pets, 4th ed., British Small Animal Veterinary Association, Gloucestershire, GB; 2002:208-222. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.249 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.9 (Nutritional/Mineral/Fluid Support Used in Reptiles.a).
· Brust DM. What every veterinarian needs to know about sugar gliders. Exotic DVM. 2009;11:32-41.; Kubiak M. Sugar gliders. In: Kubiak M, eds. Handbook of Exotic Pet Medicine; Wiley Blackwell, Oxford, UK; 2021:125-139. — Carpenter's Exotic Animal Formulary 6th ed, Table 7.5 (Miscellaneous Agents Used in Sugar Gliders).
· Carpenter JW, Klaphake E, Gibbons PM, et al. Reptile formulary. In: Divers SJ, Stahl SJ, eds. Mader's Reptile and Amphibian Medicine and Surgery, 3rd ed., Elsevier, St. Louis, MO; 2019:1191-1211. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.263 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.9 (Nutritional/Mineral/Fluid Support Used in Reptiles.a). — DRUG IDENTITY UNRESOLVED - THIS CITATION FIX DOES NOT CLOSE THE FINDING. The served 10-50 mg/kg SC, IM is printed at Carpenter 6th ed, Table 4.9 (Nutritional/Mineral/Fluid Support Used in Reptiles) under the agent heading "Calcium gluconate/borogluconate", NOT under plain "Calcium gluconate". On the SAME page the separate agent "Calcium gluconate" prints "50-100 mg/kg SC, IM, IV296" and "100 mg/kg SC, IM, ICe q6-24h32,316" for the same indication, and "Calcium glycerophosphate/calcium lactate" prints a third figure of 1-5 mg/kg. Mader 3rd ed Table 127.8 prints the identical three-way split, so this book does not treat calcium salts as interchangeable on mg/kg. Superscript 63 = Carpenter JW, Klaphake E, Gibbons PM, et al, Reptile formulary, in Mader Reptile and Amphibian Medicine and Surgery 3rd ed, 2019:1191-1211. AN EDITOR MUST DECIDE whether these two salts may share one formulary entry. No dose figure is proposed for change.
· Carpenter's Exotic Animal Formulary, 6th Ed — Carpenter's Exotic Animal Formulary, 6th ed, Table 10.1. NOTE: the served figure was matched against the table as a whole, not against this drug's own row, so confirm the number on the page before relying on it.
· Carpenter's Exotic Animal Formulary, 6th ed., Table 4.9 (Nutritional/mineral/fluid support used in reptiles), p.263 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.9 (Nutritional/Mineral/Fluid Support Used in Reptiles.a).
· Exotic Animal Emergency and Critical Care Medicine (Wiley), Guinea Pigs chapter, Toxemia of Pregnancy, printed p.299: 'Calcium gluconate 50-100 mg/kg IM (diluted 50: 50), slow IV/IO'
· Huckabee JR. Raptor therapeutics. Vet Clin North Am Exot Anim Pract. 2000;3:91-116.; Huff DG. Avian fluid therapy and nutritional therapeutics. Semin Avian Exot Pet Med. 1993;2:13-16.; Ritchie BW, Harrison GJ. Formulary. In: Ritchie BW, Harrison GJ, Harrison LR, eds. Avian Medicine: Principles and Application; Wingers Publishing, Lake Worth, FL; 1994:457-478. — Carpenter's Exotic Animal Formulary 6th ed, Table 5.11 (Nutritional/Mineral Support and Supplementation Used in Birds).
· Huff DG. Avian fluid therapy and nutritional therapeutics. Semin Avian Exot Pet Med. 1993;2:13-16. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.475 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.11 (Nutritional/Mineral Support and Supplementation Used in Birds).
· Mans C, Braun J. Update on common nutritional disorders of captive reptiles. Vet Clin North Am Exot Anim Pract. 2014;17:369-395. doi:10.1016/j.cvex.2014.05.002 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.9 (Nutritional/Mineral/Fluid Support Used in Reptiles.a).
· Mans C, Braun J. Update on common nutritional disorders of captive reptiles. Vet Clin North Am Exot Anim Pract. 2014;17:369-395. doi:10.1016/j.cvex.2014.05.002; Benne[tt] RA. Management of common reptile emergencies. Proc Annu Conf Assoc Rept Amph Vet; 1998:67-72.; McArthur SD.J, Wilkinson RJ, Barrows MG. Tortoises and turtles. In: Meredith A, Redrobe S, eds. BSAVA Manual of Exotic Pets, 4th ed., British Small Animal Veterinary Association, Gloucestershire, GB; 2002:208-222. — Carpenter's Exotic Animal Formulary 6th ed, Table 4.9 (Nutritional/Mineral/Fluid Support Used in Reptiles.a).
· Mans C, Braun J. Update on common nutritional disorders of captive reptiles. Vet Clin North Am Exot Anim Pract. 2014;17:369-395. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.263 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.9 (Nutritional/Mineral/Fluid Support Used in Reptiles.a).
· McArthur SD.J, Wilkinson RJ, Barrows MG. Tortoises and turtles. In: Meredith A, Redrobe S, eds. BSAVA Manual of Exotic Pets, 4th ed., British Small Animal Veterinary Association, Gloucestershire, GB; 2002:208-222. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.263 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.9 (Nutritional/Mineral/Fluid Support Used in Reptiles.a).
· Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.796 — Carpenter's Exotic Animal Formulary 6th ed, Table 9.6 (Emergency Drugs Used in Rodents).
· Plumb's 10th ed printed p.174-176, Calcium, IV (-Borogluconate, -Chloride, -Gluconate) monograph, Dosages.
· Plumb's Veterinary Drug Handbook, 10th ed (2023) — Plumb's 10th ed printed p.177-178, Calcium, Oral (-Carbonate, -Gluconate, -Lactate) monograph, Dosages.
· Polzin DJ, Osborne CA. Diseases of the Urinary Tract. In: Davis LE, ed. Handbook of Small Animal Therapeutics. New York: Churchill Livingstone; 1985:333-395. PMID: 42536520 — Plumb's 10th ed printed p.174-176, Calcium, IV (-Borogluconate, -Chloride, -Gluconate) monograph, Dosages.
· USPC. Veterinary Information- Appendix III. In: Drug Information for the Health Professional. Vol 2. Rockville: United States Pharmacopeial Convention; 1990:2811-2860. — Plumb's 10th ed printed p.174-176, Calcium, IV (-Borogluconate, -Chloride, -Gluconate) monograph, Dosages.