Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Vinblastine is dosed at 2 mg/m2 IV q7-14 days in dogs, per Thamm DH, Turek MM, Vail DM. Outcome and prognostic factors following adjuvant prednisone/vinblastine chemotherapy for high-risk canine mast cell tumour: 61 cases. J Vet Med Sci. 2006;68(6):581-587. doi:10.1292/jvms.68.581 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1330 (2026-08-01).. Vinblastine is used in dogs for Mast cell tumors. Routes documented in dogs: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Vinblastine in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Velban
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 2 mg/m2 | q7-14 days | 4-6 doses | Mast cell tumors | Strong | Thamm DH, Turek MM, Vail DM. Outcome and prognostic factors following adjuvant prednisone/vinblastine chemotherapy for high-risk canine mast cell tumour: 61 cases. J Vet Med Sci. 2006;68(6):581-587. doi:10.1292/jvms.68.581 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1330 (2026-08-01). |
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Enter your dog's weight to check these cited ranges in the calculator — unit and concentration math done for you.
Binds tubulin dimers preventing microtubule assembly. Arrests mitosis in metaphase. M-phase specific. Related to vincristine.
VESICANT — severe tissue necrosis with extravasation. Myelosuppression (neutropenia nadir 5-7 days). Used for mast cell tumors. Less neurotoxic than vincristine.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Vinblastine dose range in dogs, with cited source references: IV 2 mg/m2 q7-14 days. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Vinblastine in dogs: IV.
Cited course lengths for Vinblastine in dogs include: 4-6 doses. Duration depends on the indication — match it to the specific dose rule in the table above.
Vinblastine is indicated in dogs for: Mast cell tumors.
These are general warnings for Vinblastine across species; consult the dog dosing table above for species-specific guidance. VESICANT — severe tissue necrosis with extravasation. Myelosuppression (neutropenia nadir 5-7 days). Used for mast cell tumors. Less neurotoxic than vincristine.
Why a species-specific page? Vinblastine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.