ExoticRx · exoticrx.com/drugs/vinblastine
US brand names:Velban
Vinblastine is dosed at 2 mg/m2 IV q7-14 days in dogs, per Thamm DH, Turek MM, Vail DM. Outcome and prognostic factors following adjuvant prednisone/vinblastine chemotherapy for high-risk canine mast cell tumour: 61 cases. J Vet Med Sci. 2006;68(6):581-587. doi:10.1292/jvms.68.581 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1330 (2026-08-01).. Verify against current literature before clinical use.
Binds tubulin dimers preventing microtubule assembly. Arrests mitosis in metaphase. M-phase specific. Related to vincristine.
VESICANT — severe tissue necrosis with extravasation. Myelosuppression (neutropenia nadir 5-7 days). Used for mast cell tumors. Less neurotoxic than vincristine.
Species references:All Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 2 mg/m2 | q7-14 days | Strong | Thamm DH, Turek MM, Vail DM. Outcome and prognostic factors following adjuvant prednisone/vinblastine chemotherapy for high-risk canine mast cell tumour: 61 cases. J Vet Med Sci. 2006;68(6):581-587. doi:10.1292/jvms.68.581 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1330 (2026-08-01). |
Upgrade to Pro or Student to unlock the full dose ranges and frequency for every species. The drug's mechanism, warnings, indications, and cited sources are free to read.
View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.