ExoticRx · exoticrx.com/drugs/carboplatin
US brand names:Paraplatin
Carboplatin is dosed at 300 mg/m2 IV q21 days in dogs, per Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.215 (2026-08-01).. Verify against current literature before clinical use.
Platinum compound forming DNA intrastrand crosslinks and adducts inhibiting DNA replication and transcription. Cell-cycle non-specific.
Less nephrotoxic than cisplatin. Dose-limiting myelosuppression (thrombocytopenia nadir 14-21 days). FATAL IN CATS at standard dog doses. Monitor CBC.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 300 mg/m2 | q21 days | Strong | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.215 (2026-08-01). |
| Cat (Domestic) | IV | 180–240 mg/m2 | q21 days | Moderate | Kisseberth WC, Vail DM, Yaissle J, et al. Phase I clinical evaluation of carboplatin in tumor-bearing cats: a Veterinary Cooperative Oncology Group study. J Vet Intern Med. 2008;22:83-88. doi:10.1111/j.1939-1676.2007.0017.x — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.215 (2026-08-01). |
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