ExoticRx · exoticrx.com/drugs/cisplatin
US brand names:Platinol
Cisplatin is dosed at 60–70 mg/m2 IV q21 days in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Forms DNA intrastrand and interstrand crosslinks leading to cell death. Most potent platinum agent.
ABSOLUTELY CONTRAINDICATED IN CATS (fatal pulmonary edema). Aggressive saline diuresis required to prevent nephrotoxicity. Severe emesis — antiemetic protocol mandatory. Ototoxic.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 60–70 mg/m2 | q21 days | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.