ExoticRx · exoticrx.com/drugs/bleomycin
US brand names:Blenoxane
Bleomycin is dosed at 0.5–1 mg/kg Intralesional Intralesional injection q1-2 weeks in cats, per Withrow & MacEwen's Small Animal Clinical Oncology, 6th Ed. Verify against current literature before clinical use.
Generates free radicals that cause DNA strand breaks and inhibit DNA synthesis. Cell cycle specific for G2 and M phases. Concentrated in skin and lung tissue.
Pulmonary fibrosis is dose-limiting and potentially fatal. Cumulative dose limit. Anaphylaxis risk — test dose recommended. Intralesional use for squamous cell carcinoma in cats.
Species references:All Cat (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | Intralesional | 0.5–1 mg/kg | Intralesional injection q1-2 weeks | Moderate | Withrow & MacEwen's Small Animal Clinical Oncology, 6th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.