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Allergen Immunotherapy (ASIT)

Hyposensitization Injections

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Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Oncology

Routes

SCSUBLINGUAL

Indications

Atopic dermatitis

Mechanism of Action

Gradual exposure to increasing concentrations of identified allergens shifts immune response from Th2 to Th1/Treg, reducing allergic hypersensitivity.

Side effects & warnings

Risk of anaphylaxis with injections (rare). Takes 6-12 months for full effect. ~60-80% response rate in dogs. Custom formulations based on allergy testing.

Species with Allergen Immunotherapy (ASIT) dosing data (2 dose rules)

Cat (Domestic)Dog (Domestic)

Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs

Evidence levels across 2 dose rules

Strong×1Moderate×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published source

  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (2 of 2 cited rules)

A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)SC0 custom protocolSee protocol (induction/maintenance)StrongPlumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)SC0 custom protocolSee protocol (induction/maintenance)ModeratePlumb's Veterinary Drug Handbook, 9th Ed

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