Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Demecarium Bromide Ophthalmic is used in dogs for Refractory glaucoma. Routes documented in dogs: Ophthalmic. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Demecarium Bromide Ophthalmic in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Humorsol
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| Ophthalmic | Very potent long-acting miotic | 1 drop affected eye q12h-q24h | Chronic use | Refractory glaucoma | Weak | (Gum et al., 1993a) - Gelatt cites author-date, not superscript numbers; corroborated on ophtho p.1540: 'The use of demecarium bromide 0.25% topically twice daily showed a median vision retention time of 1,313 days (Binder et al., 2007).' — Verified against Veterinary Ophthalmology (Gelatt), 6th Ed, p.476 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Long-acting irreversible cholinesterase inhibitor. Produces intense, prolonged miosis and sustained reduction in intraocular pressure by enhancing trabecular outflow.
Rare — limited availability. Very potent miotic. Systemic cholinergic effects possible. Use for refractory glaucoma when other agents fail. Monitor for GI and respiratory signs.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Demecarium Bromide Ophthalmic dose range in dogs, with cited source references: Ophthalmic Very potent long-acting miotic 1 drop affected eye q12h-q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Demecarium Bromide Ophthalmic in dogs: Ophthalmic.
Cited course lengths for Demecarium Bromide Ophthalmic in dogs include: Chronic use. Duration depends on the indication — match it to the specific dose rule in the table above.
Demecarium Bromide Ophthalmic is indicated in dogs for: Refractory glaucoma.
These are general warnings for Demecarium Bromide Ophthalmic across species; consult the dog dosing table above for species-specific guidance. Rare — limited availability. Very potent miotic. Systemic cholinergic effects possible. Use for refractory glaucoma when other agents fail. Monitor for GI and respiratory signs.
Why a species-specific page? Demecarium Bromide Ophthalmic pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.