Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Neomycin is dosed at 20 mg/kg PO q8-12h in dogs, per Papich Handbook of Veterinary Drugs, 5th Ed, Neomycin, Small Animal Dosage, printed pp.559-560 (lookup pp.587-588): "Dogs and Cats • 10-20 mg/kg q6-12h PO." No per-dose reference is printed by Papich. Corroborating figure elsewhere in the cited book: plumb printed p.929 FERRETS entry "10 - 20 mg/kg PO 2 to 4 times daily". — EDITION UNVERIFIABLE 2026-08-07: this citation names Papich 5th ed, which is NOT held. Its page locator does not resolve to a page naming this drug in the held 4th ed (2016), so the reference cannot be confirmed against any copy available here. Treat the page number as unchecked and consult the 5th edition directly. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207; Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855. Neomycin is used in dogs for Hepatic encephalopathy (reduce ammonia). Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Neomycin in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Biosol
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 20 mg/kg | q8-12h | As needed for hepatic encephalopathy | Hepatic encephalopathy (reduce ammonia) | Weak | Papich Handbook of Veterinary Drugs, 5th Ed, Neomycin, Small Animal Dosage, printed pp.559-560 (lookup pp.587-588): "Dogs and Cats • 10-20 mg/kg q6-12h PO." No per-dose reference is printed by Papich. Corroborating figure elsewhere in the cited book: plumb printed p.929 FERRETS entry "10 - 20 mg/kg PO 2 to 4 times daily". — EDITION UNVERIFIABLE 2026-08-07: this citation names Papich 5th ed, which is NOT held. Its page locator does not resolve to a page naming this drug in the held 4th ed (2016), so the reference cannot be confirmed against any copy available here. Treat the page number as unchecked and consult the 5th edition directly. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207; Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 20 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.298 | 20 mg/kg p.o. q6-8h; or per rectum as a retention enema for management of acute hepatic encephalop |
| 10–20 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.588 | • 10-20 mg/kg q6-12h PO. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Binds 30S ribosomal subunit, inhibiting protein synthesis. Poorly absorbed orally; used for GI decontamination or topically.
Do NOT give parenterally (severe nephrotoxicity/ototoxicity). Oral use reduces ammonia-producing GI bacteria. Prolonged oral use may cause malabsorption.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Neomycin dose range in dogs, with cited source references: PO 20 mg/kg q8-12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Neomycin in dogs: PO.
Cited course lengths for Neomycin in dogs include: As needed for hepatic encephalopathy. Duration depends on the indication — match it to the specific dose rule in the table above.
Neomycin is indicated in dogs for: Hepatic encephalopathy (reduce ammonia).
These are general warnings for Neomycin across species; consult the dog dosing table above for species-specific guidance. Do NOT give parenterally (severe nephrotoxicity/ototoxicity). Oral use reduces ammonia-producing GI bacteria. Prolonged oral use may cause malabsorption.
Why a species-specific page? Neomycin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.