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Neomycin for Dog

Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg

Neomycin is used in dog for Hepatic encephalopathy (reduce ammonia). Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Neomycin in dog, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Biosol

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
PO10–20 mg/kgq6-12hAs needed for hepatic encephalopathyHepatic encephalopathy (reduce ammonia)ModeratePlumb's Veterinary Drug Handbook, 9th Ed

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Mechanism of action

Binds 30S ribosomal subunit, inhibiting protein synthesis. Poorly absorbed orally; used for GI decontamination or topically.

Side effects & warnings

Do NOT give parenterally (severe nephrotoxicity/ototoxicity). Oral use reduces ammonia-producing GI bacteria. Prolonged oral use may cause malabsorption.

Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Antibiotic drugs with dog dosing

Neomycin dosing in other species

Why a species-specific page? Neomycin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.