ExoticRx · exoticrx.com/drugs/neomycin
US brand names:Biosol
Neomycin is dosed at 10 mg/kg PO q 24 h in russian tortoises, per Merck Veterinary Manual. Antimicrobial Drugs Used in Reptiles (dosing table). Rahway (NJ): Merck & Co.; accessed 2026. URL: https://www.merckvetmanual.com/multimedia/table/antimicrobial-drugs-used-in-reptiles. Verify against current literature before clinical use.
Binds 30S ribosomal subunit, inhibiting protein synthesis. Poorly absorbed orally; used for GI decontamination or topically.
Do NOT give parenterally (severe nephrotoxicity/ototoxicity). Oral use reduces ammonia-producing GI bacteria. Prolonged oral use may cause malabsorption.
Species references:All African Grey Parrot drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 15 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 20 mg/kg | q8-12h | Weak | Papich Handbook of Veterinary Drugs, 5th Ed, Neomycin, Small Animal Dosage, printed pp.559-560 (lookup pp.587-588): "Dogs and Cats • 10-20 mg/kg q6-12h PO." No per-dose reference is printed by Papich. Corroborating figure elsewhere in the cited book: plumb printed p.929 FERRETS entry "10 - 20 mg/kg PO 2 to 4 times daily". — EDITION UNVERIFIABLE 2026-08-07: this citation names Papich 5th ed, which is NOT held. Its page locator does not resolve to a page naming this drug in the held 4th ed (2016), so the reference cannot be confirmed against any copy available here. Treat the page number as unchecked and consult the 5th edition directly. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207; Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855 |
| Cat (Domestic) | PO | 10–20 mg/kg | q6-12h |
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| Papich MG. Saunders Handbook of Veterinary Drugs, 4th ed (2016, held copy) — Neomycin, Small Animal Dosage, printed p.559-560 (corpus PDF p.587-588): "Dogs and Cats - 10-20 mg/kg q6-12h PO." The dosage block sits at the top of printed p.560, whose running head reads "Neostigmine" because that monograph starts lower on the page; the Neomycin monograph heading is on printed p.559. [EDITION NOTE CORRECTED 2026-08-12 — the locator DOES resolve in the held 4th edition; the earlier "EDITION UNVERIFIABLE" note was wrong and is withdrawn.] — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855 |