Which species have cited Neomycin dosing data?

Neomycin dosing in the ExoticRx formulary covers 4 species: Cat (Domestic), Cattle (Beef/Dairy), Dog (Domestic), Russian Tortoise.

Is Neomycin a controlled substance?

Neomycin is not federally scheduled in the US. Controlled-drug status differs by country — verify your local rules.

Neomycin

US brand names:Biosol

Calculate dosage

Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Neomycin is dosed at 10 mg/kg PO q 24 h in russian tortoises, per Merck Veterinary Manual. Antimicrobial Drugs Used in Reptiles (dosing table). Rahway (NJ): Merck & Co.; accessed 2026. URL: https://www.merckvetmanual.com/multimedia/table/antimicrobial-drugs-used-in-reptiles. Verify against current literature before clinical use.

Drug Class

Antibiotic

Routes

POTOPICAL

Indications

Bacterial enteritis (E. coli scours)Hepatic encephalopathyHepatic encephalopathy (reduce ammonia)

Mechanism of Action

Binds 30S ribosomal subunit, inhibiting protein synthesis. Poorly absorbed orally; used for GI decontamination or topically.

Side effects & warnings

Do NOT give parenterally (severe nephrotoxicity/ototoxicity). Oral use reduces ammonia-producing GI bacteria. Prolonged oral use may cause malabsorption.

Species with Neomycin dosing data (4 dose rules)

Cat (Domestic)Cattle (Beef/Dairy)Dog (Domestic)Russian Tortoise

Species references:All Cat (Domestic) drugs All Cattle (Beef/Dairy) drugs All Dog (Domestic) drugs All Russian Tortoise drugs

Evidence levels across 4 dose rules

Moderate×2Strong×1Weak×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 4 published sources

· FDA NADA Label
· Merck Veterinary Manual. Antimicrobial Drugs Used in Reptiles (dosing table). Rahway (NJ): Merck & Co.; accessed 2026. URL: https://www.merckvetmanual.com/multimedia/table/antimicrobial-drugs-used-in-reptiles
· Papich Handbook of Veterinary Drugs, 5th Ed, Neomycin, Small Animal Dosage, printed pp.559-560 (lookup pp.587-588): "Dogs and Cats • 10-20 mg/kg q6-12h PO." No per-dose reference is printed by Papich. Corroborating figure elsewhere in the cited book: plumb printed p.929 FERRETS entry "10 - 20 mg/kg PO 2 to 4 times daily".
· Papich Handbook of Veterinary Drugs, 5th Ed, Neomycin, Small Animal Dosage, printed pp.559-560 (lookup pp.587-588): "Dogs and Cats • 10-20 mg/kg q6-12h PO." No per-dose reference printed.

Sample dosing (2 of 4 cited rules)

A dog/cat sample is shown here. Cited dosing for all 4 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	PO	10–20 mg/kg	q6-12h	Moderate	Papich Handbook of Veterinary Drugs, 5th Ed, Neomycin, Small Animal Dosage, printed pp.559-560 (lookup pp.587-588): "Dogs and Cats • 10-20 mg/kg q6-12h PO." No per-dose reference is printed by Papich. Corroborating figure elsewhere in the cited book: plumb printed p.929 FERRETS entry "10 - 20 mg/kg PO 2 to 4 times daily".
Cat (Domestic)	PO	10–20 mg/kg	q6-12h	Moderate	Papich Handbook of Veterinary Drugs, 5th Ed, Neomycin, Small Animal Dosage, printed pp.559-560 (lookup pp.587-588): "Dogs and Cats • 10-20 mg/kg q6-12h PO." No per-dose reference printed.

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