ExoticRx · exoticrx.com/drugs/neomycin
US brand names:Biosol
Neomycin is dosed at 10 mg/kg PO q 24 h in russian tortoises, per Merck Veterinary Manual. Antimicrobial Drugs Used in Reptiles (dosing table). Rahway (NJ): Merck & Co.; accessed 2026. URL: https://www.merckvetmanual.com/multimedia/table/antimicrobial-drugs-used-in-reptiles. Verify against current literature before clinical use.
Binds 30S ribosomal subunit, inhibiting protein synthesis. Poorly absorbed orally; used for GI decontamination or topically.
Do NOT give parenterally (severe nephrotoxicity/ototoxicity). Oral use reduces ammonia-producing GI bacteria. Prolonged oral use may cause malabsorption.
Species references:All Cat (Domestic) drugsAll Cattle (Beef/Dairy) drugsAll Dog (Domestic) drugsAll Russian Tortoise drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 4 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 10–20 mg/kg | q6-12h | Moderate | Papich Handbook of Veterinary Drugs, 5th Ed, Neomycin, Small Animal Dosage, printed pp.559-560 (lookup pp.587-588): "Dogs and Cats • 10-20 mg/kg q6-12h PO." No per-dose reference is printed by Papich. Corroborating figure elsewhere in the cited book: plumb printed p.929 FERRETS entry "10 - 20 mg/kg PO 2 to 4 times daily". |
| Cat (Domestic) | PO | 10–20 mg/kg | q6-12h | Moderate | Papich Handbook of Veterinary Drugs, 5th Ed, Neomycin, Small Animal Dosage, printed pp.559-560 (lookup pp.587-588): "Dogs and Cats • 10-20 mg/kg q6-12h PO." No per-dose reference printed. |
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