Cat · Felis catus · typical adult weight 2.50–7.00 kg
Neomycin is dosed at 10–20 mg/kg PO q6-12h in cats, per Papich MG. Saunders Handbook of Veterinary Drugs, 4th ed (2016, held copy) — Neomycin, Small Animal Dosage, printed p.559-560 (corpus PDF p.587-588): "Dogs and Cats - 10-20 mg/kg q6-12h PO." The dosage block sits at the top of printed p.560, whose running head reads "Neostigmine" because that monograph starts lower on the page; the Neomycin monograph heading is on printed p.559. [EDITION NOTE CORRECTED 2026-08-12 — the locator DOES resolve in the held 4th edition; the earlier "EDITION UNVERIFIABLE" note was wrong and is withdrawn.] — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855. Neomycin is used in cats for Hepatic encephalopathy. Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Neomycin in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Biosol
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 10–20 mg/kg | q6-12h | As needed | Hepatic encephalopathy |
| Papich MG. Saunders Handbook of Veterinary Drugs, 4th ed (2016, held copy) — Neomycin, Small Animal Dosage, printed p.559-560 (corpus PDF p.587-588): "Dogs and Cats - 10-20 mg/kg q6-12h PO." The dosage block sits at the top of printed p.560, whose running head reads "Neostigmine" because that monograph starts lower on the page; the Neomycin monograph heading is on printed p.559. [EDITION NOTE CORRECTED 2026-08-12 — the locator DOES resolve in the held 4th edition; the earlier "EDITION UNVERIFIABLE" note was wrong and is withdrawn.] — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 20 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.298 | 20 mg/kg p.o. q6-8h; or per rectum as a retention enema for management of acute hepatic encephalop |
| 10–20 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.588 | • 10-20 mg/kg q6-12h PO. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Binds 30S ribosomal subunit, inhibiting protein synthesis. Poorly absorbed orally; used for GI decontamination or topically.
Do NOT give parenterally (severe nephrotoxicity/ototoxicity). Oral use reduces ammonia-producing GI bacteria. Prolonged oral use may cause malabsorption.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Neomycin dose range in cats, with cited source references: PO 10–20 mg/kg q6-12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Neomycin in cats: PO.
Cited course lengths for Neomycin in cats include: As needed. Duration depends on the indication — match it to the specific dose rule in the table above.
Neomycin is indicated in cats for: Hepatic encephalopathy.
These are general warnings for Neomycin across species; consult the cat dosing table above for species-specific guidance. Do NOT give parenterally (severe nephrotoxicity/ototoxicity). Oral use reduces ammonia-producing GI bacteria. Prolonged oral use may cause malabsorption.
Why a species-specific page? Neomycin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.