Livestock · Bos taurus · typical adult weight 250.00–900.00 kg
Neomycin is dosed at 22 mg/kg PO q24h (daily) in cattle, per FDA NADA 094-975 — NEO-TERRAMYCIN 100/100 (NEOMYCIN-OXYTETRACYCLINE) POWDER [PHIBRO ANIMAL HEALTH] — https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3e2a3dc9-6ae2-4e0c-9e2a-e1cf042c6587 NOTE: this label doses in g/head, g/lb, g/ton, mg/head, mg/lb, not mg/kg; the served figure is a unit conversion and is NOT printed verbatim on the label. Label dosing: '100 g/lb Neomycin Sulfate .' — 21 CFR § 520.1484 (Neomycin), conditions of use for Cattle, swine, sheep, and goats: 22.0462-22.0462 mg/kg (the regulation prints this per pound; converted at 2.2046226 lb/kg). Related tolerances: 21 CFR § 556.430. Retrieved from the eCFR API, snapshot 2026-01-01. https://www.ecfr.gov/current/title-21/section-520.1484 | mg/kg BASIS LOCATED 2026-08-19: Plumb's Veterinary Drug Handbook, Neomycin monograph, printed p.956, CATTLE: "Oral administration to treat and control colibacillosis (bacterial enteritis) caused by Escherichia […]" The served figure is printed for this species in this unit.. Neomycin is used in cattle for Bacterial enteritis (E. coli scours). Routes documented in cattle: PO. A typical adult cattle weighs 250.00–900.00 kg. ExoticRx lists 1 cited dose rule for Neomycin in cattle, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Biosol
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 22 mg/kg | q24h (daily) | 3-5 days | Bacterial enteritis (E. coli scours) | Weak | FDA NADA 094-975 — NEO-TERRAMYCIN 100/100 (NEOMYCIN-OXYTETRACYCLINE) POWDER [PHIBRO ANIMAL HEALTH] — https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3e2a3dc9-6ae2-4e0c-9e2a-e1cf042c6587 NOTE: this label doses in g/head, g/lb, g/ton, mg/head, mg/lb, not mg/kg; the served figure is a unit conversion and is NOT printed verbatim on the label. Label dosing: '100 g/lb Neomycin Sulfate .' — 21 CFR § 520.1484 (Neomycin), conditions of use for Cattle, swine, sheep, and goats: 22.0462-22.0462 mg/kg (the regulation prints this per pound; converted at 2.2046226 lb/kg). Related tolerances: 21 CFR § 556.430. Retrieved from the eCFR API, snapshot 2026-01-01. https://www.ecfr.gov/current/title-21/section-520.1484 | mg/kg BASIS LOCATED 2026-08-19: Plumb's Veterinary Drug Handbook, Neomycin monograph, printed p.956, CATTLE: "Oral administration to treat and control colibacillosis (bacterial enteritis) caused by Escherichia […]" The served figure is printed for this species in this unit. |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 22 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.588 | • 22 mg/kg/day PO. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
Need the exact dose for your patient?
These ranges are per kg. Enter your cattle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds 30S ribosomal subunit, inhibiting protein synthesis. Poorly absorbed orally; used for GI decontamination or topically.
Do NOT give parenterally (severe nephrotoxicity/ototoxicity). Oral use reduces ammonia-producing GI bacteria. Prolonged oral use may cause malabsorption.
Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.
Neomycin dose range in cattle, with cited source references: PO 22 mg/kg q24h (daily). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Neomycin in cattle: PO.
Cited course lengths for Neomycin in cattle include: 3-5 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Neomycin is indicated in cattle for: Bacterial enteritis (E. coli scours).
These are general warnings for Neomycin across species; consult the cattle dosing table above for species-specific guidance. Do NOT give parenterally (severe nephrotoxicity/ototoxicity). Oral use reduces ammonia-producing GI bacteria. Prolonged oral use may cause malabsorption.
Why a species-specific page? Neomycin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.